Novel ZAP-70-Related Immunodeficiency Presenting with Epstein–Barr Virus Lymphoproliferative Disorder and Hemophagocytic Lymphohistiocytosis
Zeta-chain-associated protein kinase 70 (ZAP-70) plays an integral role in the T-cell antigenic receptor complex. A deficiency of this kinase leads to a phenotype of severe combined immunodeficiency, while hypomorphic mutations of the kinase lead to more mild immunodeficiency phenotypes. We present...
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Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-01-01
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Series: | Case Reports in Immunology |
Online Access: | http://dx.doi.org/10.1155/2021/6587323 |
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