SH3GL1‐activated FTH1 inhibits ferroptosis and confers doxorubicin resistance in diffuse large B‐cell lymphoma

SH3GL1‐activated FTH1 inhibits ferroptosis and confers doxorubicin resistance in diffuse large B‐cell lymphoma

Abstract Background Diffuse large B‐cell lymphoma (DLBCL) is predominant subtype of non‐Hodgkin lymphoma and can be effectively treated. Nevertheless, a subset of patients experiences refractory or relapsed disease, highlighting the need for new therapeutic strategies. Methods Depmap database based...

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Main Authors: Zi‐Wen Duan, Wei‐Ting Wang, Yan Wang, Rong Wang, Wei Hua, Chun‐Yu Shang, Rui Gao, Hao‐Rui Shen, Yue Li, Jia‐Zhu Wu, Hua Yin, Li Wang, Jian‐Yong Li, Wei Xu, Jin‐Hua Liang
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Clinical and Translational Medicine
Subjects:
diffuse large B‐cell lymphoma
doxorubicin resistance
ferritinophagy
ferroptosis
FTH1
SH3GL1
Online Access:https://doi.org/10.1002/ctm2.70246
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https://doi.org/10.1002/ctm2.70246

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