Stereocontrolled synthesis and nuclear magnetic resonance analysis of boranophosphate/phosphate chimeric oligonucleotides

Stereocontrolled synthesis and nuclear magnetic resonance analysis of boranophosphate/phosphate chimeric oligonucleotides

This report describes the stereoselective synthesis of boranophosphate/phosphate (PB/PO) chimeric oligodeoxynucleotides (ODNs) and the nuclear magnetic resonance (NMR) analysis of oligomers containing PB linkages. This stereoselective synthesis involved dimer building blocks containing highly stereo...

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Bibliographic Details
Main Authors: Kiyoshi Kakuta, Taiichi Sakamoto, Hajime Sato, Kazuki Sato, Takeshi Wada
Format: Article
Language:English
Published: The Royal Society 2025-04-01
Series:Royal Society Open Science
Subjects:
stereoselective synthesis
boranophosphate DNA
nuclear magnetic resonance analysis
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.241797
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https://royalsocietypublishing.org/doi/10.1098/rsos.241797

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