Post-transcriptional regulation of cyclin A and B mRNAs by Bruno 1, Cup, and P-bodies

Summary: Cell cycle progression relies on tightly regulated Cyclin synthesis and degradation, with Cyclins A and B activating CDK1 to drive mitosis. Dysregulation of Cyclin levels is linked to tumorigenesis, underscoring the importance of studying cyclin mRNA control for cancer therapy development....

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Bibliographic Details
Main Authors: Livia V. Bayer, Samantha N. Milano, Harpreet Kaur, Zara Kumar, Diana P. Bratu
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225009885
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