Profiles and kinetics of PgRNA and clinical characteristics in pregnant, postpartum, and non-pregnant women with chronic HBV infection

Abstract Background Pregenomic RNA (pgRNA) has been utilized as an early predictive marker for antiviral therapy, an indicator for the emergence of drug resistance in hepatitis B virus (HBV), or a marker for safe discontinuation of nucleoside analog therapy. However, its role during pregnancy has ra...

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Bibliographic Details
Main Authors: Genju Wang, Yandan Wu, Ziyue Zhang, Qiuchen Wu, Juan Tang, Ying Ji, Yan Wang, Guanlun Zhou, Minmin Yu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Virology Journal
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Online Access:https://doi.org/10.1186/s12985-025-02871-y
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