Light-activatable manganese carbonate nanocubes elicit robust immunotherapy by amplifying endoplasmic reticulum stress-meditated pyroptotic cell death

Abstract Although tumor immunotherapy has emerged as a promising treatment modality, it faces significant challenges stemming from the immunosuppressive characteristics of the tumor microenvironment (TME), the low immunogenicity of tumors, and the poor specificity of immunoactivation. These factors...

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Main Authors: Chuan Wu, Mingquan Gao, Weidong Xiao, Xie Huang, Xinrui Yang, Zifei Wu, Xudong Yu, Banghui Mo, Zaizhi Du, Ziqian Shang, Jing Liu, Can Shi, Rong Li, Shenglin Luo, Weidong Wang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Experimental & Clinical Cancer Research
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Online Access:https://doi.org/10.1186/s13046-025-03408-5
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