A scalable platform for EPSC-Induced MSC extracellular vesicles with therapeutic potential

A scalable platform for EPSC-Induced MSC extracellular vesicles with therapeutic potential

Abstract Background Extracellular Vesicles (EVs) derived from mesenchymal stem cells (MSCs) have gained recognition as promising therapeutic and drug delivery agents in regenerative medicine. However, their clinical application is limited by donor variability, low scalability, and inconsistent thera...

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Main Authors: Shixin Gong, Nan Li, Qinqing Peng, Feng Wang, Rulong Du, Boyang Zhang, Jian Wang, Le Han, Yu Zhang, Zemin Ning, Shengjiang Tan, Yuchun Gu, Lida Wu
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Stem Cell Research & Therapy
Subjects:
Extracellular vesicles
Extended pluripotent stem cells
Induced mesenchymal stem cells
Scalable biomanufacturing
Pulmonary fibrosis therapy
Regenerative medicine
Online Access:https://doi.org/10.1186/s13287-025-04507-y
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https://doi.org/10.1186/s13287-025-04507-y

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