Sonidegib reduced tumor burden in patients with advanced basal cell carcinoma in the BOLT trial: Long-term analysis results

Sonidegib reduced tumor burden in patients with advanced basal cell carcinoma in the BOLT trial: Long-term analysis results

Background: The Hedgehog inhibitor sonidegib had durable efficacy and a manageable safety profile in patients with locally advanced basal cell carcinoma (laBCC) through 42 months of the BOLT trial. In this analysis, we characterize the effects of 200-mg and 800-mg sonidegib on tumors in patients in...

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Main Authors: Michael R. Migden, Aaron S. Farberg, James Spencer, Felix Kiecker, Alexander Guminski, Kurt Gebauer, Carmen Loquai, Caroline Robert, Reinhard Dummer, Dirk Schadendorf, Axel Hauschild, Jean Jacques Grob, Nicholas Squittieri, Ramon Arntz, Serena Martelli, Joerg Dierlamm, Ralf Gutzmer
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:EJC Skin Cancer
Subjects:
Advanced basal cell carcinoma
Hedgehog inhibitor
Locally advanced basal cell carcinoma
Sonidegib
Tumor reduction
Online Access:http://www.sciencedirect.com/science/article/pii/S2772611824002556
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http://www.sciencedirect.com/science/article/pii/S2772611824002556

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