Selective detection, quantification, and subcellular location of α-synuclein aggregates with a protein aggregate filtration assay

Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy are caused by α-synuclein aggregates. At present, there is no good biochemical method defining α-synuclein aggregates formed in vivo versus oligomers as a means to investigate α-synuclein aggregation and its...

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Bibliographic Details
Main Authors: Michael L. Kramer, Christina Behrens, Walter J. Schulz-Schaeffer
Format: Article
Language:English
Published: Taylor & Francis Group 2008-03-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/000112691
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