Efficient delivery of anlotinib and radioiodine by long circulating nano-capsules for active enhanced suppression of anaplastic thyroid carcinoma

Efficient delivery of anlotinib and radioiodine by long circulating nano-capsules for active enhanced suppression of anaplastic thyroid carcinoma

Abstract 131I therapy is clinically unfeasible for anaplastic thyroid carcinoma (ATC), due to lack of active targets and ATC’s resistance to radiation. Novel radionuclide-labeled targeted nano-drug delivery systems have exhibited the potential of prominent tumor imaging and remedy. Capitalizing on r...

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Bibliographic Details
Main Authors: Linlin Zhang, Chuanying Zhu, Shuo Huang, Miaomiao Xu, Chao Li, Hongliang Fu, Yafu Yin, Sheng Liang, Hui Wang, Zhilei Cui, Lei Huang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Nanobiotechnology
Subjects:
Anlotinib- and 131I-delivering nanoparticles
Anaplastic thyroid carcinoma (ATC)
Targeted nano-drug delivery
Efficacy
Safety
Online Access:https://doi.org/10.1186/s12951-025-03223-2
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https://doi.org/10.1186/s12951-025-03223-2

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