The impact of sulfonylureas on diverse ion channels: an alternative explanation for the antidiabetic actions

The oral hypoglycemic drug sulfonylureas exhibit substantial therapeutic benefits for millions of patients with type 2 diabetes mellitus (T2DM), although with common adverse effects, such as hypoglycemia. It is generally believed that inhibition of KATP channels by sulfonylureas in pancreatic β-cell...

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Bibliographic Details
Main Authors: Xian-Tao Li, Meng-Ze Yun
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cell and Developmental Biology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1528369/full
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