CD4+ skin resident memory T cells preferentially colocalize with dermal Folr2hi macrophages in contact hypersensitivity

In contact hypersensitivity (CHS), local immune memory is established in previously affected skin through the formation of CD4+ and CD8+ tissue-resident memory T (TRM) cells. This memory contributes to disease recurrence by enhancing local antigen responsiveness and is maintained in the long term by...

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Bibliographic Details
Main Authors: Akihiko Murata, Koji Tokoyoda
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1590687/full
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