Coupled dopamine and insulin signaling mediated transgenerational and multigenerational inheritance of adaptive traits in Caenorhabditis elegans upon parental training with Salmonella enterica Serovar Typhi

Coupled dopamine and insulin signaling mediated transgenerational and multigenerational inheritance of adaptive traits in Caenorhabditis elegans upon parental training with Salmonella enterica Serovar Typhi

ABSTRACT The nervous system’s ability to perceive and learn about the environment can help organisms evolve and acquire traits, potentially generating adaptive responses. However, its potential to produce heritable modulations is a scientific lacuna, which is under-explored. Here, with the help of C...

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Main Authors: Bynedi Seshadhri Chinna Mounish, Balasubramanian Chellammal Muthubharathi, Thirumugam Gowripriya, Koilmani Emmanuvel Rajan, Krishnaswamy Balamurugan
Format: Article
Language:English
Published: American Society for Microbiology 2025-07-01
Series:Microbiology Spectrum
Subjects:
Transgenerational inheritance
Multigenerational adaptations
Dopamine signaling
Neuronal plasticity
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02575-24
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https://journals.asm.org/doi/10.1128/spectrum.02575-24

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