Transcriptome analysis reveals PTBP1 as a key regulator of circRNA biogenesis

Transcriptome analysis reveals PTBP1 as a key regulator of circRNA biogenesis

Abstract Background Circular RNAs (circRNAs) are a class of non-coding RNAs generated through back splicing. High expression of circRNAs is often associated with numerous abnormal cellular biological processes. However, the regulatory factors of circRNAs are not fully understood. Results In this stu...

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Bibliographic Details
Main Authors: Mohan Wang, Shanshan Zheng, Yan Zhang, Jingwen Zhang, Fuming Lai, Cong Zhou, Qiangwei Zhou, Xingwang Li, Guoliang Li
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Biology
Subjects:
Circular RNAs
RNA binding proteins
PTBP1
Transcriptome
Biogenesis
Online Access:https://doi.org/10.1186/s12915-025-02233-8
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https://doi.org/10.1186/s12915-025-02233-8

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