Retinoic acid inhibition of cell proliferation via activation of CDKN1B signaling in the forebrain and spinal cord during mouse embryonic development

Retinoic acid inhibition of cell proliferation via activation of CDKN1B signaling in the forebrain and spinal cord during mouse embryonic development

Abstract Background The active metabolite of vitamin A (retinol) is retinoic acid (RA). RA is essential for developing several organs as a signaling molecule that is tightly regulated during embryogenesis. We explored the teratogenic effects of RA on forebrain and spinal cord development modified by...

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Bibliographic Details
Main Authors: Ahmed Said, Amira S. AbdElkhalek, Mariam Sherief, Lydia Amir, Maysem Samy, Mariam S. Nabil, Gehan Safwat, Ayman A. Diab, Karima Nasraldin
Format: Article
Language:English
Published: SpringerOpen 2024-11-01
Series:Beni-Suef University Journal of Basic and Applied Sciences
Subjects:
Diencephalon
Telencephalon
Spinal cord
CDKN1B
Retinoic acid
Online Access:https://doi.org/10.1186/s43088-024-00582-x
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https://doi.org/10.1186/s43088-024-00582-x

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