Leuko-glycemic Index as a Prognostic Factor after Acute Myocardial Infarction with ST-segment Elevation
<strong>Foundation:</strong> blood glucose and leukocyte count at admission have shown prognostic significance in patients with myocardial infarction. Leuko-glycemic index is a recently proposed marker as a predictor of mortality. <br /><strong>Objective:</strong> to ev...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | Spanish |
| Published: |
Universidad de las Ciencias Médicas de Cienfuegos
2019-06-01
|
| Series: | Revista Finlay |
| Subjects: | |
| Online Access: | https://revfinlay.sld.cu/index.php/finlay/article/view/636 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832577434943225856 |
|---|---|
| author | Ailed Rodríguez Jiménez Raikel Fardales Rodríguez Enrique Toledo Rodríguez Guillermo Quintana Cañizarez |
| author_facet | Ailed Rodríguez Jiménez Raikel Fardales Rodríguez Enrique Toledo Rodríguez Guillermo Quintana Cañizarez |
| author_sort | Ailed Rodríguez Jiménez |
| collection | DOAJ |
| description | <strong>Foundation:</strong> blood glucose and leukocyte count at admission have shown prognostic significance in patients with myocardial infarction. Leuko-glycemic index is a recently proposed marker as a predictor of mortality. <br /><strong>Objective:</strong> to evaluate the usefulness of the leuko-glycemic index in the stratification of the risk of in-hospital death after STEMI. <br /><strong>Method:</strong> a prospective observational study was conducted which included all patients admitted consecutively with a diagnosis of acute myocardial infarction with ST segment elevation and Killip> I class, from January 2012 to June 2015 at the Provincial University Hospital Camilo Cienfuegos Gorriarán. Clinical, laboratory and echocardiographic data were collected and the prognostic implication of the leuko-glycemic index in in-hospital mortality was determined through binary logistic regression. The studied variables were: age, sex and color of the skin, medical history and cardiovascular risk factors, clinical data such as systolic and diastolic blood pressure as well as heart rate at admission. <strong><br />Results:</strong> LGI was a predictor of mortality in both diabetic and non-diabetic patients (c = 0.673 and c = 0.707) respectively. There was a positive correlation between the Killip class and the leuco-glycemic index (r: 0.471 p <0.001). The 75th percentile showed an acceptable sensitivity and good specificity as a predictor of complications and mortality after STEMI. <br /><strong>Conclusions:</strong> the leuko-glycemic index in the course of an acute myocardial infarction can be associated with a higher in-hospital mortality. Its detection would be useful in the prognostic stratification of acute coronary syndrome. |
| format | Article |
| id | doaj-art-020b1c0f6fc643c8bde5e70cafd9a334 |
| institution | Kabale University |
| issn | 2221-2434 |
| language | Spanish |
| publishDate | 2019-06-01 |
| publisher | Universidad de las Ciencias Médicas de Cienfuegos |
| record_format | Article |
| series | Revista Finlay |
| spelling | doaj-art-020b1c0f6fc643c8bde5e70cafd9a3342025-01-30T21:21:59ZspaUniversidad de las Ciencias Médicas de CienfuegosRevista Finlay2221-24342019-06-019297107404Leuko-glycemic Index as a Prognostic Factor after Acute Myocardial Infarction with ST-segment ElevationAiled Rodríguez Jiménez0Raikel Fardales Rodríguez1Enrique Toledo Rodríguez2Guillermo Quintana Cañizarez3Hospital Provincial Universitario Camilo Cienfuegos Gorriarán. Sancti Spíritus.Hospital Provincial Universitario Camilo Cienfuegos Gorriarán. Sancti Spíritus.Hospital Provincial Universitario Camilo Cienfuegos Gorriarán. Sancti Spíritus.Hospital Provincial Universitario Camilo Cienfuegos Gorriarán. Sancti Spíritus.<strong>Foundation:</strong> blood glucose and leukocyte count at admission have shown prognostic significance in patients with myocardial infarction. Leuko-glycemic index is a recently proposed marker as a predictor of mortality. <br /><strong>Objective:</strong> to evaluate the usefulness of the leuko-glycemic index in the stratification of the risk of in-hospital death after STEMI. <br /><strong>Method:</strong> a prospective observational study was conducted which included all patients admitted consecutively with a diagnosis of acute myocardial infarction with ST segment elevation and Killip> I class, from January 2012 to June 2015 at the Provincial University Hospital Camilo Cienfuegos Gorriarán. Clinical, laboratory and echocardiographic data were collected and the prognostic implication of the leuko-glycemic index in in-hospital mortality was determined through binary logistic regression. The studied variables were: age, sex and color of the skin, medical history and cardiovascular risk factors, clinical data such as systolic and diastolic blood pressure as well as heart rate at admission. <strong><br />Results:</strong> LGI was a predictor of mortality in both diabetic and non-diabetic patients (c = 0.673 and c = 0.707) respectively. There was a positive correlation between the Killip class and the leuco-glycemic index (r: 0.471 p <0.001). The 75th percentile showed an acceptable sensitivity and good specificity as a predictor of complications and mortality after STEMI. <br /><strong>Conclusions:</strong> the leuko-glycemic index in the course of an acute myocardial infarction can be associated with a higher in-hospital mortality. Its detection would be useful in the prognostic stratification of acute coronary syndrome.https://revfinlay.sld.cu/index.php/finlay/article/view/636recuento de leucocitosglucemiapronósticoinfarto del miocardio con elevación del st |
| spellingShingle | Ailed Rodríguez Jiménez Raikel Fardales Rodríguez Enrique Toledo Rodríguez Guillermo Quintana Cañizarez Leuko-glycemic Index as a Prognostic Factor after Acute Myocardial Infarction with ST-segment Elevation Revista Finlay recuento de leucocitos glucemia pronóstico infarto del miocardio con elevación del st |
| title | Leuko-glycemic Index as a Prognostic Factor after Acute Myocardial Infarction with ST-segment Elevation |
| title_full | Leuko-glycemic Index as a Prognostic Factor after Acute Myocardial Infarction with ST-segment Elevation |
| title_fullStr | Leuko-glycemic Index as a Prognostic Factor after Acute Myocardial Infarction with ST-segment Elevation |
| title_full_unstemmed | Leuko-glycemic Index as a Prognostic Factor after Acute Myocardial Infarction with ST-segment Elevation |
| title_short | Leuko-glycemic Index as a Prognostic Factor after Acute Myocardial Infarction with ST-segment Elevation |
| title_sort | leuko glycemic index as a prognostic factor after acute myocardial infarction with st segment elevation |
| topic | recuento de leucocitos glucemia pronóstico infarto del miocardio con elevación del st |
| url | https://revfinlay.sld.cu/index.php/finlay/article/view/636 |
| work_keys_str_mv | AT ailedrodriguezjimenez leukoglycemicindexasaprognosticfactorafteracutemyocardialinfarctionwithstsegmentelevation AT raikelfardalesrodriguez leukoglycemicindexasaprognosticfactorafteracutemyocardialinfarctionwithstsegmentelevation AT enriquetoledorodriguez leukoglycemicindexasaprognosticfactorafteracutemyocardialinfarctionwithstsegmentelevation AT guillermoquintanacanizarez leukoglycemicindexasaprognosticfactorafteracutemyocardialinfarctionwithstsegmentelevation |