Assessment of periodontitis vaccine using three different bacterial outer membrane vesicles in canine model

Assessment of periodontitis vaccine using three different bacterial outer membrane vesicles in canine model

ABSTRACT Canines frequently develop periodontitis, which is similar and relevant to immunopathology and microbiology of human periodontitis. The aim of this study was to investigate whether bacterial outer membrane vesicle (OMV)-based periodontal vaccines induced humoral immune response in canines f...

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Main Authors: Ryoma Nakao, Takehiro Yamaguchi, Haruka Shibasaki, Jun Saeki, Aoi Takahashi, Ryunosuke Tominaga, Kimihiro Abe, Yukihiro Akeda, Tomoyo Nakagawa-Nakamura, Tomohiko Nishino, Kazuyuki Ishihara, Atsushi Jinno-Oue, Satoshi Inoue
Format: Article
Language:English
Published: American Society for Microbiology 2025-04-01
Series:mSphere
Subjects:
outer membrane vesicles (OMVs)
vaccines
adjuvant
periodontal disease
beagle model
Porphyromonas gingivalis
Online Access:https://journals.asm.org/doi/10.1128/msphere.01033-24
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https://journals.asm.org/doi/10.1128/msphere.01033-24

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