HYPOGLYCEMIC EFFECT OF SITAGLIPTIN AND AMINOGUANIDINE COMBINATION IN EXPERIMENTAL DIABETES MELLITUS

HYPOGLYCEMIC EFFECT OF SITAGLIPTIN AND AMINOGUANIDINE COMBINATION IN EXPERIMENTAL DIABETES MELLITUS

The aim of the work was to determine the antidiabetic effect of a sitagliptin and aminoguanidine combination in rats with experimental diabetes mellitus.Materials and methods. The study was carried out on male Wistar rats and C57BL/KsJ-db/db mice. According to the models used, it was divided into 4...

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Main Authors: D. V. Kurkin, D. A. Bakulin, E. I. Morkovin, Yu. V. Gorbunova, A. V. Strygin, T. M. Andriashvili, A. A. Sokolova, N. S. Bolokhov, V. E. Pustynnikov, E. A. Fomichev
Format: Article
Language:Russian
Published: Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute 2023-02-01
Series:Фармация и фармакология (Пятигорск)
Subjects:
dpp-4 inhibitors
sitagliptin
preclinical studies
diabetes
alloxan
streptozotocin
Online Access:https://www.pharmpharm.ru/jour/article/view/1219
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