«COCKTAIL» METHODS OF CYTOCHROME P450 ISOFORMS ACTIVITY DETERMINATION <i>IN VIVO</i> USING BIOANALYTICAL METHODS: ACTUAL METHODS REVIEW AND OPPORTUNITIES OF THEIR APPLICATION IN CLINICAL PRACTICE

The review of current «cocktail» phenotyping methods for biotransformation activity determination enabling simultaneous characterization of main cytochrome P450 isoforms activity was made. Furthermore, the possibility of their application in clinical practice in order to correct administered drugs d...

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Bibliographic Details
Main Authors: E. A. Egorenkov, V. V. Smirnov
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
Online Access:https://www.pharmjournal.ru/jour/article/view/239
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