Co-existence of two blaNDM-5 and blaOXA-181 on distinct plasmids in a carbapenem-resistant Klebsiella pneumoniae from a tertiary hospital, Tanzania

Co-existence of two blaNDM-5 and blaOXA-181 on distinct plasmids in a carbapenem-resistant Klebsiella pneumoniae from a tertiary hospital, Tanzania

Purpose: To understand the mechanisms of carbapenem-resistant Klebsiella pneumoniae (CRKP) from Tanzania and characterize the genomes carrying the carbapenemase genes. Methods: Clinical CRKP isolates were selected from ongoing antimicrobial resistance surveillance at Muhimbili National Hospital, Dar...

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Bibliographic Details
Main Authors: Lawrence Mapunda, Anthon Mwingwa, Doreen Kamori, Happiness Kumburu, Marco van Zwetselaar, Bjorn Blomberg, Joel Manyahi
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Klebsiella pneumoniae
beta-lactamase blaNDM-5
beta-lactamase OXA-181
Coexistence blaNDM-5 blaOXA-181
Plasmids Klebsiella pneumoniae
Tanzania
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716524004739
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