Nitroxoline evidence amoebicidal activity against Acanthamoeba castellanii through DNA damage and the stress response pathways

Acanthamoeba castellanii is a widespread unicellular eukaryote found in diverse environments, including tap water, soil, and swimming pools. It is responsible for severe infections, such as Acanthamoeba keratitis and granulomatous amebic encephalitis, particularly in individuals with immunocompromis...

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Bibliographic Details
Main Authors: Lijun Chen, Wei Han, Wenwen Jing, Meng Feng, Qingtong Zhou, Xunjia Cheng
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211320725000016
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