Chronic hepatitis B virus infection imbalances short-chain fatty acids and amino acids in the liver and gut via microbiota modulation

Chronic hepatitis B virus infection imbalances short-chain fatty acids and amino acids in the liver and gut via microbiota modulation

Abstract The commensal microbiota is closely related to HBV infection and HBV-related liver diseases; however, how HBV and viral components dynamically affect the targeted organ liver microbiota is not well-known. In this study, an HBV-carrier mouse model established by HBsAg+ hepatocyte replacement...

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Bibliographic Details
Main Authors: Wendi Zhang, Yuwei Wu, Min Cheng, Haiming Wei, Rui Sun, Hui Peng, Zhigang Tian, Yongyan Chen
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Gut Pathogens
Subjects:
Hepatitis B virus
HBV-carrier mouse model
Commensal microbiota
Metabolome
Online Access:https://doi.org/10.1186/s13099-025-00695-3
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https://doi.org/10.1186/s13099-025-00695-3

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