Cellular Signaling and Production of Galactose-Deficient IgA1 in IgA Nephropathy, an Autoimmune Disease
Immunoglobulin A (IgA) nephropathy (IgAN), the leading cause of primary glomerulonephritis, is characterized by IgA1-containing immunodeposits in the glomeruli. IgAN is a chronic disease, with up to 40% of patients progressing to end-stage renal disease, with no disease-specific treatment. Multiple...
Saved in:
| Main Authors: | Colin Reily, Hiroyuki Ueda, Zhi-Qiang Huang, Jiri Mestecky, Bruce A. Julian, Christopher D. Willey, Jan Novak |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
|
| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2014/197548 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
LIF/JAK2/STAT1 Signaling Enhances Production of Galactose-Deficient IgA1 by IgA1-Producing Cell Lines Derived From Tonsils of Patients With IgA Nephropathy
by: Koshi Yamada, et al.
Published: (2024-02-01) -
Lysosome-mediated aggregation of galactose-deficient IgA1 with transferrin receptor 1 links to IgA nephropathy
by: Meijun Si, et al.
Published: (2025-07-01) -
A Case of IgA Nephropathy in a Patient With Sarcoidosis: Confirmation of Glomerular Galactose-Deficient IgA1 Deposition
by: Yoshitaka Shimizu, et al.
Published: (2025-01-01) -
IgA Nephropathy in the Elderly
by: Dana V. Rizk, et al.
Published: (2025-08-01) -
GWAS for serum galactose-deficient IgA1 implicates critical genes of the O-glycosylation pathway.
by: Krzysztof Kiryluk, et al.
Published: (2017-02-01)