Myocardial Proteome in Human Heart Failure With Preserved Ejection Fraction

Myocardial Proteome in Human Heart Failure With Preserved Ejection Fraction

Background Heart failure with preserved ejection fraction (HFpEF) constitutes more than half of all HF but has few effective therapies. Recent human myocardial transcriptomics and metabolomics have identified major differences between HFpEF and controls. How this translates at the protein level is u...

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Main Authors: Vivek P. Jani, Edwin J. Yoo, Aleksandra Binek, Alina Guo, Julie S. Kim, Jennifer Aguilan, Mohammad Keykhaei, Sydney R. Jenkin, Simone Sidoli, Kavita Sharma, Jennifer E Van Eyk, David A. Kass, Virginia S. Hahn
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
fatty acids
heart failure
metabolism
myocardium
obesity
oxidative phosphorylation
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.038945
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https://www.ahajournals.org/doi/10.1161/JAHA.124.038945

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