Universal or Specific? A Modeling-Based Comparison of Broad-Spectrum Influenza Vaccines against Conventional, Strain-Matched Vaccines.

Despite the availability of vaccines, influenza remains a major public health challenge. A key reason is the virus capacity for immune escape: ongoing evolution allows the continual circulation of seasonal influenza, while novel influenza viruses invade the human population to cause a pandemic every...

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Bibliographic Details
Main Authors: Rahul Subramanian, Andrea L Graham, Bryan T Grenfell, Nimalan Arinaminpathy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-12-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1005204&type=printable
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