Effects of hydrogel stiffness and viscoelasticity on organoid culture: a comprehensive review

Abstract As an emerging technology, organoids are promising new tools for basic and translational research in disease. Currently, the culture of organoids relies mainly on a type of unknown composition scaffold, namely Matrigel, which may pose problems in studying the effect of mechanical properties...

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Bibliographic Details
Main Authors: Wei Lai, Hu Geliang, Xu Bin, Wei Wang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1186/s10020-025-01131-7
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