Low expression of miR-7-5p promotes resistance to radiotherapy in lung cancer through direct upregulation of PKP2 expression

Low expression of miR-7-5p promotes resistance to radiotherapy in lung cancer through direct upregulation of PKP2 expression

Abstract Lung cancer remains a significant global health challenge, with advanced stages often limiting surgical options and necessitating systemic therapies, such as radiotherapy. Resistance to radiotherapy frequently undermines the treatment efficacy. This study explored the role of miR-7-5p in mo...

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Bibliographic Details
Main Authors: Fan Zhang, Jiaxue Yang, Xiao-lu Qiu, Jie He, Chun Cheng, Yi Sang
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
MiR-7-5p
PKP2
NSCLC
Radiotherapy
Online Access:https://doi.org/10.1038/s41598-025-01001-6
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https://doi.org/10.1038/s41598-025-01001-6

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