Immunogenicity and vaccine efficacy of Actinobacillus pleuropneumoniae-derived extracellular vesicles as a novel vaccine candidate

Immunogenicity and vaccine efficacy of Actinobacillus pleuropneumoniae-derived extracellular vesicles as a novel vaccine candidate

Actinobacillus pleuropneumoniae (APP) is a significant pathogen in the swine industry, leading to substantial economic losses and highlighting the need for effective vaccines. This study evaluates the potential of APP-derived extracellular vesicles (APP-EVs) as a vaccine candidate compared to the co...

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Bibliographic Details
Main Authors: Su Hyun Park, Yun Hye Kim, Hyeon Jin Lee, Jeong Moo Han, Byoung-Joo Seo, Gyeong-Seo Park, Chonghan Kim, Young Bae Ryu, Woo Sik Kim
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Virulence
Subjects:
Actinobacillus pleuropneumoniae
extracellular vesicle
immunogenicity
Th1-dominant cellullar immunity
Th1-dominant humoral immunity
pre-exposure vaccine
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2025.2453818
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https://www.tandfonline.com/doi/10.1080/21505594.2025.2453818

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