Combination of the LPS/TLR4 Pathway and Fecal Metabolomics Analysis Reveals the Chronic Inflammatory Mechanism of Early Atherosclerosis in Tibetan Miniature Pigs

Combination of the LPS/TLR4 Pathway and Fecal Metabolomics Analysis Reveals the Chronic Inflammatory Mechanism of Early Atherosclerosis in Tibetan Miniature Pigs

Abstract. Objective:. This study aimed to elucidate the effect of the lipopolysaccharides/toll-like receptor 4 (LPS/TLR4) pathway on early atherosclerosis (AS) development and its associated changes in fecal metabolites, thereby providing an experimental foundation for strategies to prevent and tre...

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Main Authors: Qinqin Yang, Songtao Xu, Yueqin Cai, Yongming Pan, Junjie Huang, Keyan Zhu, Minli Chen, Xiaoping Xu, Hanjia Gao
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2025-06-01
Series:Cardiology Discovery
Online Access:http://journals.lww.com/10.1097/CD9.0000000000000153
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http://journals.lww.com/10.1097/CD9.0000000000000153

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