scVAEDer: integrating deep diffusion models and variational autoencoders for single-cell transcriptomics analysis

Abstract Discovering a lower-dimensional embedding of single-cell data can improve downstream analysis. The embedding should encapsulate both the high-level features and low-level variations. While existing generative models attempt to learn such low-dimensional representations, they have limitation...

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Bibliographic Details
Main Authors: Mehrshad Sadria, Anita Layton
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-025-03519-4
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