Rational Design and Immunological Mechanisms of Circular RNA-Based Vaccines: Emerging Frontiers in Combating Pathogen Infection

Rational Design and Immunological Mechanisms of Circular RNA-Based Vaccines: Emerging Frontiers in Combating Pathogen Infection

Vaccines remain one of the most effective tools in combating infectious diseases, though traditional platforms are constrained by limitations including suboptimal immunogenicity, safety concerns, and manufacturing complexity. Circular RNA (circRNA) vaccines have recently emerged as a novel vaccine m...

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Bibliographic Details
Main Authors: Ying Zhang, Shumei Jin, Zan Zuo, Shujing Liu, Juan Xu, Chongyi Yang, Ping Wan, Linting Xun, Mei Luo, Fan Yang, Wenjie Chen, Zhengji Song, Jialong Qi
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Vaccines
Subjects:
circRNA vaccine
circular RNA
pathogens infection
RNA delivery
Online Access:https://www.mdpi.com/2076-393X/13/6/563
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