In vivo structure profiling reveals human cytosolic and mitochondrial tRNA structurome and interactome in response to stress

Abstract Transfer RNA (tRNA) is the most abundant cellular RNA family in terms of copy numbers. It not only folds into defined structures but also has complex cellular interaction networks involving aminoacyl-tRNA synthetases, translation factors, and ribosomes. The human tRNAome is comprised of chr...

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Bibliographic Details
Main Authors: Noah Peña, Yichen Hou, Christopher P. Watkins, Sihao Huang, Wen Zhang, Christopher D. Katanski, Tao Pan
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59435-5
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