Circulating cell-free DNA methylation patterns indicate cellular sources of allograft injury after liver transplant

Circulating cell-free DNA methylation patterns indicate cellular sources of allograft injury after liver transplant

Abstract Post-transplant complications reduce allograft and recipient survival. Current approaches for detecting allograft injury non-invasively are limited and do not differentiate between cellular mechanisms. Here, we monitor cellular damages after liver transplants from cell-free DNA (cfDNA) frag...

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Main Authors: Megan E. McNamara, Sidharth S. Jain, Kesha Oza, Vinona Muralidaran, Amber J. Kiliti, A. Patrick McDeed, Digvijay Patil, Yuki Cui, Marcel O. Schmidt, Anna T. Riegel, Alexander Kroemer, Anton Wellstein
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60507-9
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https://doi.org/10.1038/s41467-025-60507-9

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