Characterization of key spike RBD residues influencing SARS-CoV-2 variant adaptation to avian ACE2

IntroductionThe beta-coronavirus SARS-CoV-2 has been revealed to infect mammals and other species, which potentially promotes the virus adaptation to broader species and the emergence of new variants. The host range of different SARS-CoV-2 variants are mainly determined by the affinity of the recept...

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Bibliographic Details
Main Authors: Weitong Yao, Yujun Li, Huize Sun, Danting Ma, Xiaojuan Tang, Aiping Zeng, Fang Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cellular and Infection Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1631926/full
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