Comparison of lipophilic and size-exclusion membranes: the effect of stirring and cyclodextrin in the donor compartment

Comparison of lipophilic and size-exclusion membranes: the effect of stirring and cyclodextrin in the donor compartment

Background and purpose: The effective transport of an active pharmaceutical ingredient across various membrane systems is critical for enhancing its bioavailability, especially in formulations involving solubilizing agents. This study aims to investigate the permeability differences of carvedilol (...

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Bibliographic Details
Main Authors: Petra Tozser, Szabina Kádár, Edina Szabó, Máté Dobó, Gergo Toth, György Tibor Balogh, Peter Soti, Bálint Sinkó, Eniko Borbas
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2025-07-01
Series:ADMET and DMPK
Subjects:
unstirred water layer
membrane transport
solubility
supersaturation ratio
carvedilol
Online Access:https://pub.iapchem.org/ojs/index.php/admet/article/view/2753
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https://pub.iapchem.org/ojs/index.php/admet/article/view/2753

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