TSH Receptor Reduces Hemoglobin S Polymerization and Increases Deformability and Adhesion of Sickle Erythrocytes

SCD is a hereditary disorder caused by genetic mutation in the beta-globin gene, resulting in abnormal hemoglobin, HbS that forms sickle-shaped erythrocytes under hypoxia. Patients with SCD have endocrine disorders and it was described that 7% of these patients have clinical hypothyroidism. Recent s...

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Bibliographic Details
Main Authors: Evelyn Mendonça-Reis, Camila Cristina Guimarães-Nobre, Lyzes Rosa Teixeira-Alves, Leandro Miranda-Alves, Clemilson Berto-Junior
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Anemia
Online Access:http://dx.doi.org/10.1155/2024/7924015
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