Isolation and characterization of human cKIT positive amniotic fluid stem cells obtained from pregnancies with spina bifida

Isolation and characterization of human cKIT positive amniotic fluid stem cells obtained from pregnancies with spina bifida

Abstract Myelomeningocele (MMC) and myeloschisis (MS) are considered as the most severe forms of spina bifida aperta characterized by incomplete closure of the neural tube during the first trimester of pregnancy. Open maternal-fetal surgery has been identified as a promising alternative for the repa...

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Main Authors: Katarzyna Michalak-Micka, Nadine Huerlimann, Nicole Ochsenbein-Kölble, Martin Ehrbar, Agnes Silvia Klar, Thomas Biedermann, Ueli Moehrlen
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
Subjects:
Amniotic fluid
Amniotic fluid stem cells
Spina bifida aperta
Myelomeningocele
Myeloschisis
Online Access:https://doi.org/10.1038/s41598-025-03518-2
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https://doi.org/10.1038/s41598-025-03518-2

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