Recent emergence of cephalosporin-resistant Salmonella Typhi in India due to the endemic clone acquiring IncFIB(K) plasmid encoding blaCTX-M-15 gene

Recent emergence of cephalosporin-resistant Salmonella Typhi in India due to the endemic clone acquiring IncFIB(K) plasmid encoding blaCTX-M-15 gene

ABSTRACT The emergence and spread of Salmonella Typhi (S. Typhi) resistant to third-generation cephalosporins is a serious global health concern. In this study, we genomically characterized 142 cephalosporin-resistant S. Typhi strains isolated from India. Comparative genome analysis revealed the eme...

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Main Authors: Tharani Priya Thirumoorthy, Jobin John Jacob, Aravind Velmurugan, Monisha Priya Teekaraman, Bhavini Shah, Veena Iyer, Geeti Maheshwari, Urmi Trivedi, Anand Shah, Pooja Patel, Anushree Gaigawale, Yesudoss M, Pavithra Sathya Narayanan, Ankur Mutreja, Megan Carey, Jacob John, Gagandeep Kang, Balaji Veeraraghavan
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:Microbiology Spectrum
Subjects:
cephalosporin resistant
Salmonella Typhi
genome analysis
plasmid
antimicrobial resistance
India
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00875-24
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https://journals.asm.org/doi/10.1128/spectrum.00875-24

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