Case Report: A rare case of ALK-KIF5B gene fusion benefited from treatment with lorlatinib

The anaplastic lymphoma kinase (ALK) gene encodes a transmembrane receptor tyrosine kinase. Most mutations in ALK gene result from translocations with other genes, forming fusion oncogenes. To date, 21 different genes have been identified as ALK fusion partners, each activating distinct signaling pa...

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Bibliographic Details
Main Authors: Yuxi Luo, Weiwei Ouyang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1594072/full
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