The role of NAD+ metabolism and its modulation of mitochondria in aging and disease

Abstract Nicotinamide adenine dinucleotide (NAD+) is a coenzyme involved in a plethora of physiological reactions, with a key relevance in supporting mitochondrial function. Due to its critical role in these cellular processes, declining levels of NAD+ are associated with general aging and chronic d...

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Bibliographic Details
Main Authors: Khalishah Yusri, Sandra Jose, Karen S. Vermeulen, Trina Chia Min Tan, Vincenzo Sorrentino
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:npj Metabolic Health and Disease
Online Access:https://doi.org/10.1038/s44324-025-00067-0
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