Aberrant gene expression in the diagnosis of childhood leukemias not characterized by -involved cytogenetic abnormalities

The AML1 ( acute myeloid leukemia 1 ) gene, a necessary prerequisite of embryonic hematopoiesis and a critical regulator of normal hematopoietic development, is one of the most frequently mutated genes in human leukemia, involving over 50 chromosome translocations and over 20 partner genes. In the f...

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Bibliographic Details
Main Authors: Maria Adamaki, Spiros Vlahopoulos, George I Lambrou, Athanasios G Papavassiliou, Maria Moschovi
Format: Article
Language:English
Published: SAGE Publishing 2017-03-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317694308
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