Pharmacokinetics of post-transplant cyclophosphamide and its associations with clinical outcomes in pediatric haploidentical hematopoietic stem cell transplantation by Kyung Taek Hong, Sungyeun Bae, Yoon Sunwoo, Juyeon Lee, Hyun Jin Park, Bo Kyung Kim, Jung Yoon Choi, Joo-Youn Cho, Kyung-Sang Yu, Jaeseong Oh, Hyoung Jin Kang

“…Results A total of 15 pediatric patients (median age at HSCT 9.6 years, range 1.6–16.8) were enrolled. Thirteen patients had malignant disease. …”
Get full text

Impact of Hepatic Steatosis on the Antiviral Effects of PEG-IFNα-2a in Patients with Chronic Hepatitis B and the Associated Mechanism by Huiqing Liang, Yaoyu Liu, Xiaoqian Jiang, Xiaoting Zheng, Jinmo Tang, Jiaen Yang, Hongli Zhuang, Penghua Lai, Li Peng, Zhenying Guo, Shanshan Cai, Dan Luo, Lingxia Xu, Qianguo Mao, Shaodong Chen

“…Hepatic steatosis can reduce the efficacy of PEG-IFNα-2a in the treatment of CHB patients, and its mechanism may be related to the different HBcAg expression patterns in liver tissue.…”
Get full text

Dynamic changes and drives of surface urban heat islands in China by Qiumeng Zhang, Baoquan Jia, Tong Li, Yarong Yang, Youxin Fang

“…This study leveraged long-term MODIS land surface temperature data, delving into the temporal variations and spatial patterns of surface urban heat island intensity (SUHII) across 1444 counties in China from both annual and seasonal time scales, as well as from national and climatic zone spatial dimensions. …”
Get full text

Global research trends and focus on immunotherapy for endometrial cancer: a comprehensive bibliometric insight and visualization analysis (2012-2024) by Yachen Xu, Yachen Xu, Yachen Xu, Yachen Xu, Tao Wang, Xiaojing Liang, Xiaojing Liang, Xiaojing Liang, Xiaojing Liang, Jie Yang, Jie Yang, Jie Yang, Jie Yang, Yuxiang Zhang, Yuxiang Zhang, Yuxiang Zhang, Yuxiang Zhang, Shan Bao, Shan Bao, Shan Bao, Shan Bao

“…Bibliometric tools, CiteSpace and VOSviewer, were used to analyze clustering patterns and research dynamics.ResultsA total of 861 articles were contributed by 5,331 authors from 1,392 institutions across 58 countries or regions, involving 1,823 keywords. …”
Get full text

The Effect of Probiotics on Preterm Birth Rates in Pregnant Women After a Threatened Preterm Birth Episode (The PROPEV Trial) by Ester del Barco, Leidy-Alejandra G. Molano, Mireia Vargas, Marta Miserachs, Linda Puerto, Carmen Garrido-Giménez, Zaida Soler, Begoña Muñoz, Laia Pratcorona, Sonia Rimbaut, Mercè Vidal, Marta Dalmau, Alba Casellas, Elena Carreras, Chaysavanh Manichanh, Maria Goya

“…Although mortality rates have decreased, morbidity rates remain concerningly high. In recent years, there has been a surge in studies examining the etiology, risk factors, and management of preterm birth. …”
Get full text

Mental health burden of persons living in Ukraine and Ukrainians displaced to Switzerland: the mental health assessment of the Ukrainian population (MAP) studies by Anja Frei, Milo A Puhan, Viktor von Wyl, Susi Kriemler, Mariya Bachmaha, Erich Seifritz, Tala Ballouz, Viktoriia Yasenok, Andreas Michael Baumer, Viktoriia Petrashenko, Marco Kaufmann, Seraina Rüegger, Andrii Loboda, Vladyslav Smiianov, Orest Suvalo, Andriana Kostenko

“…We observed consistent patterns: (1) The burden was higher in south-east and central Ukraine than in the north-west; (2) refugee mental health closely resembles that of south-eastern and central Ukraine; (3) prevalences among women were higher than for men across conditions.To contextualise differences in mental health burden, we highlight the example of the group of old women aged 25–44 years. …”
Get full text

Resistome and Phylogenomics of <i>Escherichia coli</i> Strains Obtained from Diverse Sources in Jimma, Ethiopia by Mulatu Gashaw, Esayas Kebede Gudina, Guenter Froeschl, Ralph Matar, Solomon Ali, Liegl Gabriele, Amelie Hohensee, Thomas Seeholzer, Arne Kroidl, Andreas Wieser

“…<b>Introduction</b>: In recent years, antimicrobial resistance (AMR) rates have increased significantly in bacterial pathogens, particularly extended beta-lactam resistance. …”
Get full text

Anthromes and forest carbon responses to global change by J. Aaron Hogan, Jeremy W. Lichstein, Eileen H. Helmer, Matthew E. Craig, Evan Fricke, Viola Henrich, Steven A. Kannenberg, Charles D. Koven, Kees Klein Goldewjik, David M. Lapola, Yue Li, Yadvinder Malhi, John Quinn, Stephanie Roe, Cesar Terrer, Emilio Vilanova, Anthony P. Walker, Kai Zhu, Erle C. Ellis

“…Summary Human effects on ecosystems date back thousands of years, and anthropogenic biomes—anthromes—broadly incorporate the effects of human population density and land use on ecosystems. …”
Get full text

Allergen immunotherapy in Italy: How, when, and why—A real-world study conducted through a patient association by Giovanni Paoletti, MD, Emanuele Nappi, MD, Maria Chiara Bragato, MD, Paola Valli, MD, Mattia Giovannini, MD, Domenico Gargano, MD, Luca Pecoraro, MD, Deborah Diso, MSc, Simona Barbaglia, MSc, Giorgio Walter Canonica, MD, Enrico Heffler, MD, PhD

“…Understanding AIT utilization patterns might disclose information about why it is underused, thus providing valuable insights on how to broaden the positive impact it can have on the population. …”
Get full text

Genetic profiling of extended-spectrum β-Lactamase and carbapenemase-producing Escherichia coli O157:H7 from clinical samples among diarrheal patients in Shashemene, Ethiopia by Shimelis Teshome Ayalneh, Biruk Yeshitela Beshah, Yeonji Jeon, Ashenafi Alemu Wami, Seifegebriel Teshome, Solomon Gebreselassie, Se Eun Park, Mekonnen Teferi, Woldaregay Erku Abegaz

“…These isolates were obtained from clinical stool samples and (9/27) 33.3% of the isolates were from under five years children, predominantly from urban areas, and those that have contact with domestic animals. …”
Get full text

Atividade lenta posterior: correlação eletro-clínica Posterior EEG slow activity: electro-clinical correlation by Salustiano Gomes Lins

“…The absense of a significant association between the Pi waves and the theta rhythm suggests that these two electrical patterns are related to quite autonomous phenomena.…”
Get full text

Factors associated with the serum 25-hydroxyvitamin D levels in adults by Sue-Hsien Chen, Shu-Ching Chen, Yo-Ping Lai, Pin-Hsuan Chen, Kun-Yun Yeh

“…Methods A cross-sectional study recruiting 4,457 adults, aged over 18 years, was conducted between August 2019 and December 2023. …”
Get full text

Embodying disadvantage: a theoretically-informed analysis of pathways linking socioeconomic position with all-cause and cancer mortality in a nationally representative cohort of ad... by Dana Lee Olstad, Sara Nejatinamini, Seyed Hosseini Pozveh, Jenny Godley, Gavin R. McCormack, Lin Yang, Tolulope T. Sajobi

“…Methods This was a prospective, population-based cohort study of adults (≥ 35 years; n = 308,635) who participated in the cross-sectional Canadian Community Health Survey. …”
Get full text

Immunophenotyping of colon cancer for identification of potential antigens for colon cancer vaccines by Xuan Wang, Xuan Wang, Jingjiang Lai, Dawei Wang, Keyi Wei, Jing Yang

“…BackgroundColon cancer is a prevalent malignancy that significantly threatens human health. In recent years, mRNA cancer vaccines have demonstrated considerable potential and distinct advantages in colon cancer treatment. …”
Get full text

Estimation of duration and its changes in Lagrangian observations relying on ice floes in the Arctic Ocean utilizing a sea ice motion product by F. Zhang, F. Zhang, R. Lei, R. Lei, M. Qu, N. Li, Y. Chen, X. Pang

“…Ice trajectory terminal points did not reveal an obvious long-term tendency, but they were regulated by large-scale atmospheric circulation patterns, especially those in the early drifting stage in autumn (OND). …”
Get full text

Cumulative behavioral and metabolic determinants of health are associated with higher inflammation-related indices: insights from a cross-sectional study (NHANES 2005–2018) by Anzhi Wang, Youping Zeng, Xiaoyan Gao, Xunge Lin, Shenshen Du, Ping Wang, Yun Pan

“…Multivariable-adjusted logistic regression models examined dose–response relationships, with trend analysis explicitly testing cumulative BDoH-MDoH interactions.ResultsThe cohort (mean age 44.3 ± 0.3 years; 52.4% male) demonstrated significant positive associations between adverse health determinants and inflammatory indices. …”
Get full text

Management practices and mortality predictors among Klebsiella pneumoniae infections across Lebanese hospitals: a multicenter retrospective study by Rania Itani, Hani M. J. Khojah, Hamza Raychouni, Rahaf Kibrit, Patricia Shuhaiber, Carole Dib, Mariam Hassan, Tareq L. Mukattash, Abdalla El-Lakany

“…Emphasis should be placed on enhancing the monitoring of local resistance patterns and using these data to guide the selection of appropriate empirical therapy to reduce mortality associated with K. pneumoniae infections.…”
Get full text

Biodiversity and Abundance of Angiosperms and Environmental Resilience in the Tidal Range of Yuanjiang Dry–Hot Valley, Southwestern China by Fengchun Yang, Qiong He, Huaping Huang, Yanmei Cui, Jianyong Gou, Chaya Sarathchandra, Kritana Prueksakorn, Kiyota Hashimoto, Li Liu

“…This study explored the relationship between diversity patterns of plant species and their environments in the lowland of this dry–hot valley. …”
Get full text

Prevalence and determinants of prehypertension (elevated blood pressure or high normal BP) according to different classifications in India during 2015-2021: Evidence from the large... by Geetu Singh, Renu Agrawal, Sanjeev Kumar, Shubham Kumar, Rudresh Negi, Sonu Goel, Tanya Agarwal

“…We also calculated Moran's Index to explain the data's overall clustering and project the strength and patterns of spatial autocorrelation to represent district-level results.…”
Get full text

Health Care Workers’ Perspectives on the Barriers and Facilitators to Digital Health Technology Use to Support Symptomatic Cancer Diagnosis in Southern Africa: Qualitative Study by Kirsten D Arendse, Sarah Day, Bothwell Takaingofa Guzha, Tasleem Ras, Valerie Anne Sills, Natalie Tegama, Jennifer Moodley, Fiona M Walter, Suzanne E Scott

“…ResultsThe median age of participants was 44 (IQR 34‐53) years, 38 (68%) were female, and most were nurses (n=34, 61%) or doctors (n=18, 32%). …”
Get full text