Feasibility and efficacy of real-time teleresistance exercise programs for physical function in elderly patients after hip fracture surgery: a randomized controlled trial by Piyapat Dajpratham, Jidapa Komas, Rungsima Yamthed, Prasertphon Chanthon, Kriangkrai Kovintaset, Thaniyaporn Claikhem, Aasis Unnanuntana, Ekasame Vanitcharoenkul, Varalak Srinonprasert, Unchana Sura-amonrattana

“…Abstract Background Hip fractures substantially impair quality of life and functional outcomes in elderly individuals. With incidence rates rising globally and in Thailand, effective rehabilitation strategies are crucial. …”
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Left atrial energy loss as a novel predictor of mortality and cardiovascular events in chronic kidney disease patients with preserved ejection fraction by Xiaoxue Chen, Daoqin Li, Wei Wang, Zhengqin Qi, Kun Xue, Lijuan Sun, Chengyu Yang, Xuejie Shen, Degang Song

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THE FREQUENCY OF SARCOPENIA IN OLDER AGE GROUPS: EVALUATION OF DIAGNOSTIC CRITERIA by Yu. A. Safonova, E. G. Zotkin

“…With age, the frequency of sarcopenia increased, reaching 52.9% among people over 85 years of age. Muscle strength measurement versus other functional tests is a more sensitive diagnostic method for sarcopenia.…”
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Factors Associated with the Severity of Stress Urinary Incontinence in Elderly Women by Suting Li, Zhi Wang, Lian Yang, Shaoying Liu, Lili Jing, Li Hong

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Prevalence of Chronic Obstructive Pulmonary Disease and Asthma in the Community of Pathumthani, Thailand by Narongkorn Saiphoklang, Pitchayapa Ruchiwit, Apichart Kanitsap, Pichaya Tantiyavarong, Pasitpon Vatcharavongvan, Srimuang Palungrit, Kanyada Leelasittikul, Apiwat Pugongchai, Orapan Poachanukoon

“…Being elderly, smoking, having heart disease, and experiencing any respiratory symptoms with a history of treatment are crucial indicators for these airway diseases. Pulmonary function testing might be needed for active surveillance to detect these respiratory diseases in the community.…”
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Association of patent ductus arteriosus treatment in extremely low gestational age neonates with two year kidney outcomes: a secondary analysis of the preterm erythropoietin neurop... by Paige E. Condit, Ronnie Guillet, Dinushan Kaluarachchi, Russell L. Griffin, Shina Menon, David J. Askenazi, Matthew W. Harer

“…Little is known about how different management approaches to a PDA, either conservative management or active management and either medical or surgical treatment, in preterm neonates impact kidney function over the longer term. The objective of this study is to evaluate rates of kidney dysfunction at two years of age in extremely low gestational age neonates (ELGANs) with treated compared to untreated PDAs. …”
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Physical activity complexity, cognition, and risk of cognitive impairment and dementia in the Baltimore Longitudinal Study of Aging by Yurun Cai, Junhong Zhou, Paul W. Scott, Qu Tian, Amal A. Wanigatunga, Lewis Lipsitz, Eleanor M. Simonsick, Susan M. Resnick, Luigi Ferrucci, Dianxu Ren, Jennifer H. Lingler, Jennifer A. Schrack

“…METHODS A total of 637 older adults (age 73.9 ± 11.3 years) in the BLSA completed a 7‐day wrist‐worn accelerometer assessment and neuropsychological tests from 2015 to 2020. …”
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Effects of physically active lessons and active breaks on cognitive performance and health indicators in elementary school children: a cluster randomized trial by João Carlos N. Melo, Julian Tejada, Ellen Caroline M. Silva, José Ywgne, David N. Oliveira, Larissa Gandarela, Danilo R. Silva

“…Cognitive function was measured via reaction time and correct responses on computerized tests (Go/NoGo, DigitSpan, Mental Rotation, Visual Search, and Cueing Posner). …”
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Transcriptomic Signature of Frailty in Older Patients With Cardiovascular Disease Undergoing Cardiac Surgery or TAVI by Omar Baritello, Simon H. Sündermann, Kristian Espinosa‐Garnica, Jörg Kempfert, Markus Jähnert, Nick L. Beetz, Dominik Geisel, Jasmin Gaugel, Julia Rominger, Ursula Müller‐Werdan, Catrin Herpich, Kristina Norman, Alexandra Chadt, Hadi Al‐Hasani, Heinz Völler, Annett Salzwedel, Heike Vogel

“…ABSTRACT Background Deterioration of functional capacity mostly determinates frailty in older patients with cardiovascular disease (CVD). …”
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Long-term outcomes of mesenchymal stem cell therapy in severe COVID-19 patients: 3-year follow-up of a randomized, double-blind, placebo-controlled trial by Meng-Qi Yuan, Le Song, Ze-Rui Wang, Zi-Ying Zhang, Ming Shi, Junli He, Qiong Mo, Ning Zheng, Wei-Qi Yao, Yu Zhang, Tengyun Dong, Yuanyuan Li, Chao Zhang, Jinwen Song, Lei Huang, Zhe Xu, Xin Yuan, Jun-Liang Fu, Cheng Zhen, Jianming Cai, Jinghui Dong, Jianzeng Zhang, Wei-Fen Xie, Yonggang Li, Bo Zhang, Lei Shi, Fu-Sheng Wang

“…Both groups showed similar results for total lung severity scores (TSS), 6-MWD, pulmonary function tests, and Long COVID symptoms. No significant differences between groups were observed in new-onset complications (including tumorigenesis) or tumor marker levels. …”
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Biological Activity and Structure–Activity Relationship of Functionalized Thiols Against <i>Leishmania major</i>, the Agent of Human Cutaneous Leishmaniasis by Taylor Henne, Linsey Curry, Kenlei Gunther, Cameron Smith, Hannah Braunstein, Abdikani Omar Farah, Timothy K. Beng, Blaise Dondji

“…Of the 21 compounds tested, 13 were active against <i>L. major</i> promastigotes in vitro at 100 μg/mL. …”
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Understanding autism spectrum disorder and social functioning in children with neurofibromatosis type 1: protocol for a cross-sectional multimodal study by Kathryn N North, Marc Seal, Vicki Anderson, Kristina M Haebich, Natalie A Pride, Karin S Walsh, Anita Chisholm, Melissa Rouel, Alice Maier, Tim Silk, Mayuresh Korgaonkar, Francesca Lami, Jennifer Lorenzo, Gabriel Dabscheck, Caroline D Rae, Michael Kean, Jonathan M Payne

“…Participants will be 200 children with NF1 (3–15 years of age), 70 TD participants (3–15 years) and 35 children with idiopathic ASD (7–15 years). …”
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Psychometric evaluation of the NoMAD instrument in cancer care settings: assessing factorial validity, measurement invariance, and differential item functioning by Maja Kuharic, James Lorenz Merle, David Cella, Sandra A. Mitchell, Lisa DiMartino, Jennifer L. Ridgeway, Don S. Dizon, Roshan Paudel, Jessica D. Austin, Sandra L. Wong, Ann Marie Flores, Andrea L. Cheville, Justin D. Smith, the IMPACT Consortium

“…Measurement invariance was tested across research centers, professional roles, and years in current roles using multi-group CFA. …”
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Normative Values of Retinal Nerve Fibre Layer Thickness and Optic Nerve Head Parameters and Their Association with Visual Function in an African Population by Stephen Ocansey, Emmanuel Kwasi Abu, Andrew Owusu-Ansah, Shadrack Mensah, John Oduro-Boateng, Rene Abalo Kojo, Samuel Kyei, Samuel Bert Boadi-Kusi, Obed Amoah-Smith, Enyam Komla Amewuho Morny, Charles Darko-Takyi, Carl Halladay Abraham, Benjamin Appiah Nyamekye, Alex Azuka Ilechie

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Echocardiographic assessment of left ventricular function in mules under general anesthesia induced with a high-dose xylazine-based protocol by Pannawat Puangsubsin, Ashannut Isawirodom, Porrakote Rungsri, Nuttapon Satumay, Aree Laikul, Worakij Cherdchutham

“…Given the unique pharmacokinetics in mules and their higher anesthetic requirements, this study aimed to assess the effects of acepromazine-xylazine-diazepam-ketamine anesthesia, using the upper limit xylazine dose (1.6 mg/kg), on the left ventricular size and function in mules. Materials and Methods: Six healthy adult mules (18.83 ± 0.75 years; 263.83 ± 39.34 kg) were evaluated using standard two-dimensional and M-mode transthoracic echocardiography. …”
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Prioritization of candidate cancer drugs based on a drug functional similarity network constructed by integrating pathway activities and drug activities by Jieyi Di, Baotong Zheng, Qingfei Kong, Ying Jiang, Siyao Liu, Yang Yang, Xudong Han, Yuqi Sheng, Yunpeng Zhang, Liang Cheng, Junwei Han

“…Due to the speed, efficiency, relative risk, and lower costs compared to traditional drug discovery, the prioritization of candidate drugs for repurposing against cancers of interest has attracted the attention of experts in recent years. Herein, we present a powerful computational approach, termed prioritization of candidate drugs (PriorCD), for the prioritization of candidate cancer drugs based on a global network propagation algorithm and a drug–drug functional similarity network constructed by integrating pathway activity profiles and drug activity profiles. …”
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The Influence of Interatrial Conduction Disorders on Atrial Mechanical Function — Atrial Strain and Pulmonary Veins Reversal Flow in Patients with COVID-19 by Jacek Zawadzki, Jacek Gajek, Grzegorz Zawadzki, Agnieszka Sławuta, Bartosz Kudliński

“…Methods: The study included 51 patients who tested positive for SARS-CoV-2 and exhibited related symptoms. …”
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Introducing a volume change function in process-based modelling of soil development due to land management: A proof of concept by Hamza Chaif, Saba Keyvanshokouhi, Peter Finke, Cédric Nouguier, Nicolas Moitrier, Nicolas Beudez, Sophie Cornu

“…Both versions of the model (constant and changing volume) were tested. Soil dilation was predicted over the top soil (<15 cm) when the tillage practices were reduced. …”
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Characterization and functional analysis of BRCA1 and BRCA2 variants in a cohort of 100 unselected patients undergoing germline screening by Qianqian Shi, Jinshuang Gao, Haiyang Yu, Yaodong Niu, Erfeng Yuan, Yaqing Guo, Liying Song, Yang Fang, Yu Wang, Enwu Yuan, Yanwu Zhang, Xin Zhao, Linlin Zhang

“…Our study identified six novel BRCA mutations and functionally validated the pathogenicity of the BRCA2 p.W2619C variant, thereby advancing the understanding of BRCA-related cancer risk and supporting enhanced genetic counseling and testing strategies for at-risk populations.…”
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Development of the children's primitive reflex integration assessment scale by Meng Wang, Jing Yu, Hongyao Li, Chongran Zhao, Yichao Li, Xinyue Yang

“…Item Discrimination Method (IDM), Critical Ratio Method (CRM), and Internal Consistency Coefficient Method (ICCM) were used for item analysis of pilot testing data. For formal testing data, Cronbach's α assessed the reliability of the scale, while fit indices such as chi-square value/degrees of freedom (χ2/df), Root Mean Square Error of Approximation (RMSEA), and Comparative Fit Index (CFI), along with tests of construct validity, evaluated the scale's validity.ResultsOverall, 555 participants were selected, 234 children with a mean age of 7.59 ± 0.71 years participated in the pilot testing, while 321 children with a mean age of 7.73 ± 0.71 years participated in the formal testing. …”
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