Longitudinal DNA methylation profiles in saliva of offspring from mothers with gestational diabetes: associations with early childhood growth patterns by Teresa M. Linares-Pineda, Alfonso Lendínez-Jurado, Alberto Piserra-López, María Suárez-Arana, María Pozo, María Molina-Vega, María José Picón-César, Sonsoles Morcillo

“…Correlation analysis examined associations between methylation and growth variables (weight, height, BMI and annual growth) using Spearman tests. Results We identified 6,968 DMPs at the postpartum stage and 5,132 after one year, with 50 sites remaining differentially methylated over time, 16 of which maintained consistent methylation directionality. …”
Get full text

Non-classical pulmonary exacerbation in cystic fibrosis revealing ALK-Translocated lung cancer: A case report by Mohamad Hadhud, Johnathan Arnon, Anat Hershko-Moshe, Adi Hollander, Noa Hurvitz-Lehmann, Assaf Potruch, Henny Azmanov, Rottem Kuint, Nurith Hiller, Elie Picard, Naama Sebbag-Sznajder, Shira Leebhoff, Michael Wilschanski, Myriam Grunewald, Liron Birimberg-Schwartz, Malena Cohen-Cymberknoh

“…A trial of Elexacaftor/Tezacaftor/Ivacaftor (ETI) led to significant clinical improvement and enhanced pulmonary function. In vitro testing using patient-derived intestinal organoids was performed in parallel and also demonstrated a significant response to ETI. …”
Get full text

Pragmatic posterior capsular stretch and its effects on shoulder joint range of motion by Keramat Ullah Keramat, Muhammad Naveed Babur

“…Inclusion criteria were grade 1 and grade 2 of the shoulder mobility test of functional movement screening. Preintervention and postintervention measurement of flexion, abduction, internal rotation (IR), external rotation (ER), reaching up behind the back (RUBTB) and reaching down behind the neck (RDBTN) were compared. …”
Get full text

The Role of Infection in Acute Exacerbation of Idiopathic Pulmonary Fibrosis by Dong Weng, Xian-Qiu Chen, Hui Qiu, Yuan Zhang, Qiu-Hong Li, Meng-Meng Zhao, Qin Wu, Tao Chen, Yang Hu, Liu-Sheng Wang, Ya-Ru Wei, Yu-Kui Du, Shan-Shan Chen, Ying Zhou, Fen Zhang, Li Shen, Yi-Liang Su, Martin Kolb, Hui-Ping Li

“…Mortality of AE-IPF in one year (39.5%) was higher compared to stable IPF (28.7%).Conclusions. …”
Get full text

Feasibility and inter-rater reliability of physical performance measures in acutely admitted older medical patients. by Ann Christine Bodilsen, Helle Gybel Juul-Larsen, Janne Petersen, Nina Beyer, Ove Andersen, Thomas Bandholm

“…The mean± SD age was 78±8.3 years, and 73.1% were women. All patients performed grip strength and Cumulated Ambulation Score testing, 81% performed the gait speed test, and 54% completed the 30-s chair stand test (46% were unable to rise without using the armrests). …”
Get full text

Effect of Tiotropium Bromide on Airway Inflammation and Programmed Cell Death 5 in a Mouse Model of Ovalbumin-Induced Allergic Asthma by Juan Wang, Xiaolin Diao, Hong Zhu, Bei He

“…The impact of tiotropium was assessed by histology of lung tissue and morphometry. Pulmonary function was tested by using pressure sensors. The number of cells in bronchoalveolar lavage fluid (BALF) was detected. …”
Get full text

Current perspectives on neuromodulation in ALS patients: A systematic review and meta-analysis. by Ana M Jiménez-García, Gaspard Bonnel, Alicia Álvarez-Mota, Natalia Arias

“…The functionality of ALS was also different (p = 0.007), but not the quality of life. …”
Get full text

A novel mutation, Ile344Asn, in microsomal triglyceride transfer protein abolishes binding to protein disulfide isomerase by Swati Valmiki, Cindy Bredefeld, M. Mahmood Hussain

“…Genetic testing revealed biallelic variants in the MTTP gene. …”
Get full text

Neither source nor trap: Urban gardens as habitat for nonmigratory monarch butterflies in Northern California by E. Erickson, C. B. Schultz, E. E. Crone

“…However, it is not clear whether urban environments function as high‐quality habitat as opposed to demographic sinks or ecological traps. …”
Get full text

Effectiveness of scapular clock exercises in scapular dyskinesia in post operative cardiac patients: A randomized clinical trial by Izza Ayub, Sana Zahir, Aqsa Shahid, Rohail Amir Babar, Amir Mushtaq

“…Statistical analysis was conducted using RM-ANOVA and independent t-tests. Results: The mean age of n=17(60%) male and n=11(40%) female subjects were 55.21±7 years. …”
Get full text

The Efficacy of Combined Use of Huaier Granules in the Treatment of Primary Liver Cancer: An Updated Systematic Review and Meta-Analysis by Tianhui Zhou, Yingying Zhang, Yuqing Lu, Zhaodong Sun, Dehui Wang, Xiaolong Zhang, Yu Wang, Yinuo Wei, Tiange Zhang, Xin Zhang, Ruohan Wei, Po Hu, Guangming Yang, Xinzhu Wang, Yang Pan

“…<b>Results:</b> Heterogeneity testing and analysis using a random-effects model showed that the combination of Huaier granules and conventional treatment significantly reduced the recurrence rate (OR = 0.65, 95% CI 0.50–0.85, <i>p</i> = 0.002) and improved the one-year survival rate (OR = 0.79, 95% CI 0.65–0.96, <i>p</i> = 0.02). …”
Get full text

Prevalence of chronic obstructive pulmonary disease in high-risk populations at low, intermediate, high altitudes: a population based cross-sectional study in Yunnan Province, Chin... by Geyi Wen, Jinliang Meng, Huadan Wang, Puxian Peng, Yanyan Xu, Ruiqi Wang, Zhengmao Yan, Bangyan Du, Aihan Wen, Guohong Luo, Wenlong Cui, Songyuan Tang, Yunhui Zhang

“…Screening questionnaires identified high-risk individuals among participants, who then underwent pulmonary function tests. COPD was diagnosed based on post-bronchodilator test results. …”
Get full text

TP53 Mutation Predicts Worse Survival and Earlier Local Progression in Patients with Hepatocellular Carcinoma Treated with Transarterial Embolization by Ken Zhao, Anita Karimi, Luke Kelly, Elena Petre, Brett Marinelli, Erica S. Alexander, Vlasios S. Sotirchos, Joseph P. Erinjeri, Anne Covey, Constantinos T. Sofocleous, James J. Harding, William Jarnagin, Carlie Sigel, Efsevia Vakiani, Etay Ziv, Hooman Yarmohammadi

“…The time to progression with death or the last patient contact without progression as competing risks were used to obtain a cumulative incidence function, and the association with TP53 status was evaluated using the Gray test. …”
Get full text

Analysis of some error-causing factors in two-dimensional geoelectrical studies and providing a solution to minimize them by Hosein Moghaddasi, Mohsen Moghaddasi, Ahmad Neyamadpour

“…In recent years, two-dimensional geoelectrical surveys have become one of the common and conventional methods in mineral exploration, groundwater resources investigations, engineering geophysics, archeology, etc. …”
Get full text

Asociación entre variables antropométricas y calidad de movimientos fundamentales en una muestra de escolares chilenos entre 12 y 14 años (Association between anthropometric varia... by Francisca Mora Lavados, Valentina Pérez Naiman, Catalina Pacheco Concha, Manuel Andrés Monrroy Uarac, Mauricio San-Martín Correa, Rubén Gajardo Burgos

“…Material and method: Observational cross-sectional study. 18 children (11 males) of 12.72 ± 0.57 years old were assessed. Weight, height, body mass index, waist perimeter, hip perimeter, waist-to-hip, and waist-to-height indexes and percentage of adipose tissue were evaluated, and the Functional Movement Screen (FMS) to determine the quality of fundamental movements was applied. …”
Get full text

Motor symptoms and the quality of life of relapsing-remitting multiple sclerosis patients in a specialized center in South of Brazil by Francielle Fontana Jorge, Alessandro Finkelsztejn, Luciano Palmeiro Rodrigues

“…Methods: Fifty five patients at the Neuroimmunology Outpatient Clinic of the Hospital de Clínicas de Porto Alegre were evaluated for fatigue (Fatigue Severity Scale — FSS), walking ability (Functional Ambulation Categories — FAC), impact of MS on walking (Multiple Sclerosis Walking Scale-12 — MSWS-12), walking speed (10-Meter Walk Test — 10MWT and the Times 25-foot Walk test — T25FW), functional independence (Barthel Index — BI), functional mobility (Timed Up and Go — TUG), and quality of life (Multiple Sclerosis Impact Scale — MSIS-29). …”
Get full text

DigiBete, a Novel Chatbot to Support Transition to Adult Care of Young People/Young Adults With Type 1 Diabetes Mellitus: Outcomes From a Prospective, Multimethod, Nonrandomized Fe... by Veronica Swallow, Janet Horsman, Eliza Mazlan, Fiona Campbell, Reza Zaidi, Madeleine Julian, Jacob Branchflower, Jackie Martin-Kerry, Helen Monks, Astha Soni, Alison Rodriguez, Rob Julian, Paul Dimitri

“… Abstract BackgroundTransition to adult health care for young people and young adults (YP/YA) with type 1 diabetes mellitus (T1DM) starts around 11 years of age, but transition services may not meet their needs. …”
Get full text

Transcriptomics-Based Study of Immune Genes Associated with Subclinical Mastitis in Bactrian Camels by Wanpeng Ma, Huaibin Yao, Lin Zhang, Yi Zhang, Yan Wang, Wei Wang, Yifan Liu, Xueting Zhao, Panpan Tong, Zhanqiang Su

“…This study focused on 7-year-old Bactrian camels and collected 2 mL of blood from the camels that tested positive with a 4-peak California Mastitis Test (CMT) and those that tested negative with a 3-peak CMT. …”
Get full text

Single, double, and triple-hit strategies to establish a long-term premature rabbit model of bronchopulmonary dysplasia by Chiara Catozzi, Francesca Stretti, Enrica Scalera, Matteo Storti, Angelo Modena, Giorgio Aquila, Gino Villetti, Erica Ferrini, Andrea Grandi, Franco Fabio Stellari, Francesca Ravanetti, Luisa Ragionieri, Roberta Ciccimarra, Matteo Zoboli, Christina Brandenberger, Henri Schulte, Xabier Murgia, Maurizio Civelli, Francesca Ricci

“…The BPD rabbit model exposed to 95% oxygen has been used in recent years for drug testing. However, the toxicity of the strong hyperoxic hit precludes a longer-term follow-up due to high mortality after the first week of life. …”
Get full text

Prospective study of factors associated with asthma attack recurrence (ATTACK) in children from three Ecuadorian cities during COVID-19: a study protocol by Cristina Ardura-Garcia, Max Bachmann, Alejandro Rodriguez, Philip Cooper, Michael Richard Perkin, Irina Chis Ster, Natalia Cristina Romero, Martha E Chico, Alvaro Cruz, Diana Morillo, Santiago Mena-Bucheli, Angélica Ochoa, Claudia Rodas, Augusto Maldonado, Karen Arteaga, Jessica Alchundia, Karla Solorzano, Camila Figueiredo

“…In addition, the following are being measured at baseline and during follow-up: lung function and reversibility by spirometry before and after salbutamol; fractional exhaled nitric oxide (FeNO); and presence of IgG antibodies to SARS-CoV-2 in blood. …”
Get full text