C1qtnf6 Expression as a Prognostic Biomarker and Therapeutic Target in Lung Adenocarcinoma: Implications for Immune Infiltration and Tumor Progression by Qincai Li, Hua Zhang, Hai Yun‐Liu, Peifeng Zheng, Xiaogang Xu

“…ABSTRACT Background The incidence and mortality of lung cancer are increasing every year, making it the primary cause of cancer‐related fatalities globally. …”
Get full text

Analysis of capacity load and nutritional status of peritoneal dialysis patients with diabetic kidney disease and non diabetic kidney disease by BAI Tian-li, YU Qing, ZHU Bing-bing, WANG Yun-man, WANG Hao

“…Objective To analyze the changes of capacity load and nutritional status of diabetic kidney disease(DKD) and non diabetic kidney disease(NDKD) patients within one year of peritoneal dialysis,so as to provide theoretical basis for better clinical intervention.Methods The general data of 116 patients(42 in DKD group and 74 in NDKD group) who received peritoneal dialysis(PD) in our hospital from January 2010 to August 2019 were collected by retrospective analysis.The indexes of laboratory tests such as liver function and brain natriuretic peptide were measured at baseline and 1,3,6,12 months after PD;and clinical evaluation indexes such as peritoneal dialysis mode,dialysate concentration and dosage,24-hour ultrafiltration volume,24-hour urine volume,blood pressure,edema,and types of antihypertensive drugs were compared within a group and between groups by statistical tools,so as to clarify PD efficacy and the efficacy difference between the two groups.Results The dosage of peritoneal dialysis in the DKD group was higher than that in NDKD group(P<0.05) at various time points one month after dialysis.There was no significant difference in 24-hour peritoneal ultrafiltration volume(P>0.05),but 24-hour urine volume in the DKD group was less than that in the NDKD group(P<0.05),the incidence of edemat was higher than that of NDKD group(P<0.05) after 12 months of dialysis,but there was no significant difference in blood pressure level and types of antihypertensive drugs taken(P>0.05).After treatment,serum albumin(Alb) in the study population was lower than that at baseline(P<0.05),and Alb in the DKD group was lower than that in the NDKD group(P<0.05) from baseline to six months after dialysis.There was no significant difference between the two groups after six months(P>0.05).Conclusions The nutritional status in the DKD group is worse than that in the NDKD group at the early stage of dialysis.After 12 months of dialysis,the patients in the DKD group are in a higher capacity load condition than those in the NDKD group.After 1 month of dialysis,the DKD group needs a bigger peritoneal dialysis dosage than the NDKD group.This suggests that clinicians should make a reasonable peritoneal dialysis plan according to their body fluid retention,blood pressure and other factors to maintain an appropriate blood volume and protect residual renal functions.…”
Get full text

Factors associated with changes in walking performance in individuals 3 months after stroke or TIA: secondary analyses from a randomised controlled trial of SMS-delivered training... by Staffan Eriksson, Erik Lundström, Birgit Maria Vahlberg, Ulf Holmback

“…Inclusion criteria were patients aged 18 or above and the major eligibility criterion was the ability to perform the 6 min walking test.Intervention The intervention group received standard care plus daily mobile phone text messages (short message service) with instructions to perform regular outdoor walking and functional leg exercises in combination with step counting and training diaries. …”
Get full text

Survival differences according to baseline characteristics of patient with advanced heart failure treated with levosimendan by Angel-Alberto Garcia-Peña, Alejandro Mariño, Oscar-Mauricio Muñoz-Velandia, Daniela Saa-González

“…A total of 39.5% died during 1-year follow-up. Survival functions were worse in patients with N-terminal pro-brain natriuretic peptide levels >6000 pg/mL (HR: 2.72; 95% CI: 1.01–8.01, p  = 0.0493). …”
Get full text

Development of Wellness Culture through corrective gymnastics by Darinka Ignatova

“…The students in the study group are heterogeneous, showing progress in different tests. At the end of the school year, some students show no progress in results or maintain the levels from the beginning of the school year. …”
Get full text

Assessment of return to play after an acute shoulder injury: protocol for an explorative prospective observational German multicentre study by Leonard Achenbach, Hendrik Bloch, Eduard Kurz, Ines Buchholz, Dirk Maier, Arthur Praetorius, Sebastian Seyler, Susanne Standtke

“…The functional tests comprise handgrip strength, upper quarter Y-balance test, isometric strength, closed kinetic chain upper extremity stability test, wall hop test, functional throwing performance index and the unilateral seated shot put test and isokinetic tests.Ethics and dissemination The results of this study will be disseminated through peer-reviewed publications and scientific presentations at national and international conferences. …”
Get full text

Depressive disorders in elderly patients with heart failure disease by I. V. Osipova, N. V. Pogosova, Y. V. Sokolova

“…In 105 hospitalized patients with Functional Class I‑III CHF (NYHA), mean age 77,5±4,7 years, depressive disorder severity (CES‑D scale), quality of life, QoL (Minnesota Questionnaire), physical functioning (6‑minute walk test) were assessed at admission and after 3 weeks of CHD treatment, without antidepressant therapy. …”
Get full text

Neuromuscular transmission deficits in patients with CMT and ClC‐1 inhibition in CMT animal models by Thomas Skjærlund Grønnebæk, Helga Haahr‐Lillevang, Martin Skov, Kristina Kelly, Nathan R. Kerr, Jose A. Viteri, Andrea Jaworek, Amy Bartlett, Jane Bold, John Hutchison, Jorge Quiroz, Hatice Tankisi, Thomas Holm Pedersen, Henning Andersen, William David Arnold

“…Results Twenty‐one CMT patients (46.4 ± 14.4 years) and 10 HC (43.3 ± 12.7 years) were enrolled. …”
Get full text

Evaluation of a national digital pre-implantation biopsy service for deceased-donor kidney transplantation in the UK (Pithia trial); a stepped-wedge cluster randomised registry tri... by Dominic M. Summers, John O.O. Ayorinde, Desley A. Neil, Karla Hemming, Laura Smith, Jennifer Mehew, Helen Thomas, Rosie Brown, Suzie Phillips, Emma Laing, Anna Sidders, Alison J. Deary, Rachel J. Johnson, Victoria Bardsley, Sathia Thiru, Meryl H. Griffiths, Ranmith Perera, Owen Cain, Candice Roufosse, Naomi Simmonds, Michael Sheaff, Natalie Brearley, Bindu Vydianath, Anna Paterson, Kishore Gopalakrishnan, Anastasios Chatzitolios, Chris J. Callaghan, Richard Jarvis, Frank J.M.F. Dor, Smarajit Dutta, Atul Bagul, Colin Wilson, Dan Ridgway, Adam Barlow, Richard Baker, Adnan Sharif, James McDaid, John Terrace, Lorna Marson, Debabrata Roy, James Hunter, Laszlo Szabo, Simon Knight, Karen Stevenson, Patrick Mark, Samuel Turner, Zia Moinuddin, Abbas Ghazanfar, Rajesh Sivaprakasam, Reza Motallebzadeh, Nicholas Torpey, Gareth Jones, Catherine Boffa, Paul Gibbs, Andrew Connor, Imran Saif, Badri Shrestha, Harry Hill, James Fotheringham, Gavin J. Pettigrew

“…Summary: Background: Pre-implantation biopsy may help select kidneys retrieved from elderly deceased donors for transplantation, but concerns persist that it may cause unnecessary discard of kidneys that would have provided acceptable transplant function. The PITHIA trial tested the hypothesis that introduction of a National Digital Pathology Service (NDPS) would increase the proportion of kidneys transplanted from elderly donors and/or improve their function. …”
Get full text

Psychophysiological correlates of attitudes to illness and stressovercoming behavior of patients with ischemic heart disease at the step of preparation for coronary artery bypass g... by A. V. Solodukhin, O. A. Trubnikova, M. S. Yanitsky, A. V. Sery, O. L. Barbarash

“…The psychological status was diagnosed using the questionnaire «Type of attitude to the disease», the test «Strategies for coping-behavior» of Lazarus and psychophysiological indicators using the diagnostic complex «Status PF»: complex visual-motor reaction, level of functional mobility of the nervous processes, volume of attention, distribution of attention using the Bourdon Corrective Test, memory 10 numbers test, memory 10 syllables test, memory 10 words test, figurative memory, brain performance. …”
Get full text

METAB‐HTX: prospective, longitudinal cohort study evaluating cardiac and systemic metabolism after heart transplantation by Amin Polzin, Daniel Scheiber, Fabian Voss, Jean Haurand, Elric Zweck, Daniel Oehler, Oliver Maier, Mareike Cramer, Maximilian Spieker, Constanze Moos, Ursala Tokhi, David Naguib, Philipp Mourikis, Marcel Benkhoff, Robert Wagner, Michael Roden, Heinz‐Peter Schultheiss, Sascha Dietrich, Hug Aubin, Udo Boeken, Artur Lichtenberg, Malte Kelm

“…The METAB‐HTX trial will address these open questions, hypothesizing that metabolic deterioration post‐HTX is associated with impaired cardiac function and survival. Methods and results METAB‐HTX is a prospective, longitudinal cohort study, enrolling 400 patients post‐HTX in a period of 5 years. …”
Get full text

The pipB Gene as Target for Development of Detection Method of Pathogenic Bacteria Salmonella typhi Using Real-time Polymerase Chain Reaction by Muktiningsih Nurjayadi, Gusti Angieta Putri, Ananda Indah Putri Sihombing, Puan Aqila Azizah, Anisa Fitriyanti, Royna Rahma Musie, Helzi Angelina, Grace, Agus Setiawan, Dandy Akbar Juliansyah, Jefferson Lynford Declan, Gladys Indira Putri, Siti Fatimah, Adinda Myra Amalia Putri, Vira Saamia, Irma Ratna Kartika, Fera Kurniadewi, Shyi-Tien Chen, Bassam Abomoelak, Hesham A. El Enshasy

“…The pipB gene of Salmonella typhi has the function of being an autophagia inhibitor in humans. …”
Get full text

Prospective association between social engagement and cognitive impairment among middle-aged and older adults: evidence from the China Health and Retirement Longitudinal Study by Zhi-Jie Zheng, Yinzi Jin, Shuduo Zhou, Suhang Song

“…This study aimed to examine the association of social engagement with cognitive decline during the process of normal ageing.Methods We used data from the China Health and Retirement Longitudinal Study. The cognitive functions were tested at baseline, and 2-year and 4-year follow-up visits. …”
Get full text

The effects of regular training on spinal posture: a fitness and bodybuilding perspective by Mustafa Bingöl, Şaban Ünver, Hakkı Mor, Yunus Berk, Tülay Ceylan, Deniz Günay Derebaşı, Yağmur Naz Aydın, Tülin Akman, Hamza Küçük, Levent Ceylan

“…BackgroundRegular training is associated with better postural alignment, decreased risk of musculoskeletal problems, and improved overall physical function. The aim of this study was to examine the changes in the spinal postures of individuals who regularly engage in fitness and bodybuilding training.MethodsA total of 252 male individuals between the ages of 20–28 (mean age: 23.71 ± 1.81 years), who either engage in fitness and bodybuilding training (athletes) (n = 125; age 23.61 ± 1.78 years; sports age 5 ± 0.89 years) and those who do not engage in sports (sedentary) (n = 127; age 23.82 ± 1.83 years) participated in the study. …”
Get full text

A 14-week structured breathing program: an investigation into its impact on psychological health parameters in university students by Alexandru Florian Crișan, Camelia Corina Pescaru, Adelina Maritescu, Vlad Carunta, Emil Robert Stoicescu, Cristian Oancea, Elena Amăricăi, Roxana Ramona Onofrei

Get full text

Nurse's Knowledge about Modifiable and Non-Modifiable Risk Factors of Heart Failure Patient in Erbil Teaching Hospitals by Yousif Mohammed Younis

“…Data was analysis by the statistical package for science service (SPSS version 17) was used for data entering and analysis such as S= significant (<0.05), very highly significant (<0.000) and non-significant (>0.05), Percentage, frequency and Chi-square test were used to interpretation. Results: According to the results, that majority of the sample (67.2%) were within age group 23-32 years old. …”
Get full text

The peak oxygen uptake of healthy Turkish children with reference to age and sex: a pilot study by Yeşim Gürsel, Birkan Sonel, Haydar Gök, Peyman Yalçin

“…There were no differences in all of the test parameters with reference to sex except in the age group of 13 years. …”
Get full text

Reliability and validity of the Clinical pHysical rEsilience assEssment Scale (CHEES) in community-dwelling older adults by Yiwen Xing, Pan Liu, Wenhua Yu, Yiwei Zhao, Zhibin Wang, Yue Wu, Xue Gao, Yu Wang, Yansu Guo, Yumin Wang, Yi Tang, Lina Ma

“…Background: Physical resilience is closely related to healthy aging and refers to the ability of an individual to recover or maintain function after a stressor. However, tools for assessing physical resilience among community-dwelling older adults in China are lacking. …”
Get full text

Docosahexaenoic acid and adult memory: a systematic review and meta-analysis. by Karin Yurko-Mauro, Dominik D Alexander, Mary E Van Elswyk

“…Docosahexaenoic acid (DHA; 22:6 n-3) is a long-chain polyunsaturated fatty acid (LCPUFA) and an integral part of neural membrane phospholipids that impacts brain structure and function. Past research demonstrates a positive association between DHA plasma status/dietary intake and cognitive function.…”
Get full text

Differences in Cortical Activation During Dorsiflexion and Plantarflexion in Chronic Ankle Instability: A Task-fMRI Study by Xu Wang MD, Xiang Geng, Zhifeng Wang

“…A uniplanar and nonweightbearing ankle dorsiflexion-plantarflexion paradigm (a recognized model or pattern) was performed using a short-block design during the functional MRI scan.The cerebral excitability patterns between patients with chronic ankle instability and controls were analyzed using t-tests.Spearman analysis was performed to explore the correlation between activation regions and the three clinical assessment scales. …”
Get full text