Case Report Cognitive impairment in elderly population is not always a dementia by Karolina Narejko, Martyna Niemczuk, Maksymilian Adam Lech, Sylwia Koziej, Agnieszka Kasiukiewicz, Zyta Beata Wojszel

“…Considering the multi-disease nature and complexity of the treatment process for the geriatric population, it is crucial to exclude the several other disease processes and to actively search for causes of cognitive impairment, especially reversible conditions whose treatment can significantly improve cognitive function. DESCRIPTION OF THE CASE An 89-year-old man was admitted to the Geriatrics Unit due to progressive cognitive impairment and motor signs with the suspected dementia diagnosis. …”
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Prevalence of Cognitive Impairment Amongst Older Adults and the Associated Risk Factors by Zana Faris Muhammed, Ali Hattem Hussain, Haitham Assem Abdalrazak

“…Further, mini mental state examination tool to assess cognitive function, activities of daily living tool to assess physical functional capacity, patient health questionnaire-9 tool to identify depressive symptoms, Snellen chart to examine visual acuity and whispered voice test to examine hearing acuity were used.  …”
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Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predict... by Caroline A. Brorsson, Lotte B. Nielsen, Marie Louise Andersen, Simranjeet Kaur, Regine Bergholdt, Lars Hansen, Henrik B. Mortensen, Flemming Pociot, Joachim Størling, Hvidoere Study Group on Childhood Diabetes

“…The clinical impact of these loci on β-cell function during disease progression is unknown. We aimed at testing whether a genetic risk score could predict glycemic control and residual β-cell function in type 1 diabetes (T1D). …”
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Estimation of Static Lung Volumes and Capacities From Spirometry Using Machine Learning: Algorithm Development and Validation by Scott A Helgeson, Zachary S Quicksall, Patrick W Johnson, Kaiser G Lim, Rickey E Carter, Augustine S Lee

“…ResultsA total of 121,498 pulmonary function tests were used in this study, with 85,017 allotted for exploratory data analysis and model development (ie, training dataset) and 36,481 tests reserved for model evaluation (ie, testing dataset). …”
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Changes in the Patient-Reported Outcomes Measurement Information System (PROMIS) scores following sacral neuromodulation for lower urinary tract symptoms by Elaine Minerva Jaworski, Derrick J. Sanderson, Matthew Gevelinger, Paula J. Doyle

“…The difference between pre- and post-procedure PROMIS scores was compared via two-sided Wilcoxon signed-rank test, with p <0.05 considered statistically significant. …”
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Long-term cognitive effects of menopausal hormone therapy: Findings from the KEEPS Continuation Study. by Carey E Gleason, N Maritza Dowling, Firat Kara, Taryn T James, Hector Salazar, Carola A Ferrer Simo, Sherman M Harman, JoAnn E Manson, Dustin B Hammers, Frederick N Naftolin, Lubna Pal, Virginia M Miller, Marcelle I Cedars, Rogerio A Lobo, Michael Malek-Ahmadi, Kejal Kantarci

“…The LGM revealed significant associations between intercepts and slopes for cognitive performance across almost all domains, indicating that cognitive factor scores changed over time. Tests assessing the effects of mHT allocation on cognitive slopes during the KEEPS and across all years of follow-up including the KEEPS Continuation visit were all statistically nonsignificant. …”
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Effect of <i>CTLA4</i> gene polymorphism on relapse probability among patients with acute leukemias after allogenic hematopoietic stem cells transplantation by D. S. Romaniuk, A. A. Khmelevskaya, M. Yu. Drokov, N. N. Popova, V. A. Vasilieva, L. A. Kuzmina, G. A. Efimov, E. N. Parovichnikova, V. G. Savchenko

“…Polymorphisms in the CTLA4 gene can affect its function and the efficiency of the antitumor response. …”
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Protocol and research program of the European registry and biobank for interstitial lung diseases (eurILDreg) by Ekaterina Krauss, Silke Tello, Jennifer Naumann, Sandra Wobisch, Clemens Ruppert, Stefan Kuhn, Poornima Mahavadi, Raphael W. Majeed, Philippe Bonniaud, Maria Molina-Molina, Athol Wells, Nik Hirani, Carlo Vancheri, Simon Walsh, Matthias Griese, Bruno Crestani, Andreas Guenther, on behalf of further eurILDreg investigators, RARE-ILD investigators

“…Methods The foundation of eurILDreg is built on a comprehensive parameter list developed and adopted by clinical experts, encompassing over 1,800 distinct parameters related to patient history, clinical examinations, diagnosis, lung function and biospecimen collection. This robust dataset is further enriched with daily assessments captured through the patientMpower app, including handheld spirometry and exercise tests, conducted on approximately 350 patients over the course of a year. …”
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Sarcoidosis causing goiter; a case report with literature review by Abdulwahid M. Salih, Aras J. Qaradakhy, Ari M. Abdullah, Yadgar A. Saeed, Aso S. Muhialdeen, Abdullah A. Qadir, Shko H. Hassan, Goran L. Omer, Imad J. Habibullah, Fahmi H. Kakamand

“…Physical examination revealed an enlarged, firm, and non-tender thyroid gland. Thyroid function tests were normal, with a high level of angiotensin-converting enzyme. …”
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Case report and review of the literature: a unique presentation of Blau syndrome in a Palestinian family by Sandra Subhi Hnaihen, Nofouz I. A. Maswada, Aya Ahmad Bahar, Mayar Idekedek, Fawzy M. Abunejma, Fawzy M. Abunejma

“…Blau syndrome (BS) is a rare inherited systemic disorder, attributed to a gain-of-function mutation in the nucleotide-binding oligomerization domain (NOD2) gene, which results in the upregulation of pro-inflammatory cytokines. …”
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Pengaruh Keragaman Penggunaan Lahan di Ekosistem Gambut sub DAS Kapuas Kabupaten Kubu Raya by Rima Wahyu Utami, Kartini Kartini, Aji Ali Akbar

“…The effect of conversion on water quality in land, fear with pH parameters ranging from 3.3 to 4.6, TSS ranging from 6-440 mg / l and DO ranging from 0.89-3.4 mg / l which are not in accordance with the specified quality standards namely Class 2 PP No. 82 Year 2001. Conversion of peatlands is increasing every year and affects the socio-economic conditions of the community with the social function of absorption of labor and the economic function of income from agricultural production. …”
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Opportunities for immunocorrection aiming for reduction of morbidity in the areas with adverse occupational and environmental conditions by S. V. Petlenko, E. G. Golovacheva, O. I. Afanasieva

“…Following the immunotropic therapies, the subjects showed an increase in relative content of CD3+, CD4+, and CD8+ subpopulations, normalization of functional oxygen-dependent metabolism of polymorphonuclear neutrophil granulocyte system in the NBT test, as well as harmonization of the content of serum immunoglobulin contents. …”
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Lifetime estrogen exposure and domain-specific cognitive performance: results from the IGNITE study by Amber Watts, Amber Watts, Shannon Donofry, Shannon Donofry, Hayley Ripperger, Nicole M. Eklund, Lu Wan, Chaeryon Kang, George Grove, Lauren E. Oberlin, Lauren E. Oberlin, Swathi Gujral, Eric D. Vidoni, Jeffrey M. Burns, Edward McAuley, Edward McAuley, Charles H. Hillman, Arthur F. Kramer, Arthur F. Kramer, M. Ilyas Kamboh, Kirk I. Erickson, Kirk I. Erickson

“…Future work should evaluate causal mechanisms of associations between lifetime estrogen exposure and later life cognitive function.…”
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Reversible Wenckebach Phenomenon in a Young Patient with Dengue Fever: A Case Report by Subash Mohan Thulasi, Yohidha Balamurugan, Sornavalli Valliappan, Visvesvaran Salitteeswaran, PK Ananthakumar

“…A previously healthy 22-year-old male presented with intermittent fever, chills, generalised myalgia, gastrointestinal symptoms and dehydration for five days. …”
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Kimura disease, a rare Ethiopian case report by Yohannis Derbew Molla, Hirut Tesfahun Alemu, Kassa Berie Zegeye, Tiruzer Bekele, Amanuel Kassa Tadesse, Isak Omer Answar

“…Investigations showed pneumonia, elevated renal function tests and kimura disease. Unfortunately, the patient signed medical advice before completing her management. …”
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Ebstein Anomaly in Pregnancy by Lusiani Rusdi, Syahrir Azizi, Christopher Suwita, Astrid Karina, Sally A Nasution

“… A 27-year-old primiparous woman with 28 weeks gestational age was admitted to our hospital with worsening shortness of breath. …”
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Secondary Squamous Cell Carcinoma of the Tongue Complicated with Bronchiolitis Obliterans as a Manifestation of Graft-versus-Host Disease following Peripheral Blood Stem Cell Trans... by Kengo Hashimoto, Toru Nagao, Shin Koie, Satoru Miyabe, Terumi Saito

“…Biopsy of this lesion confirmed SCC (cT2N0M0). Pulmonary function testing for general anesthesia was almost normal. …”
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Ebstein Anomaly in Pregnancy by Lusiani Rusdi, Syahrir Azizi, Christopher Suwita, Astrid Karina, Sally A Nasution

“… A 27-year-old primiparous woman with 28 weeks gestational age was admitted to our hospital with worsening shortness of breath. …”
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Estradiol-to-testosterone ratio and erectile dysfunction in men aged 35-45 by Georgi V. Lazarov

“…In the clinical examination of these patients, it is necessary to test for estradiol in addition to testosterone.…”
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Hereditary Hypercalcemia Caused by a Homozygous Pathogenic Variant in the CYP24A1 Gene: A Case Report and Review of the Literature by Daniele Cappellani, Alessandro Brancatella, Martin Kaufmann, Angelo Minucci, Edda Vignali, Domenico Canale, Elisa De Paolis, Ettore Capoluongo, Filomena Cetani, Glenville Jones, Claudio Marcocci

“…Introduction. Loss of function mutations of CYP24A1 gene, which is involved in vitamin D catabolism, cause vitamin D-mediated PTH-independent hypercalcemia. …”
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