Evaluation of e-Lung automated quantitative computed tomography biomarkers in idiopathic pulmonary fibrosis by Peter M. George, Christian Rennison-Jones, Giacomo Benvenuti, Aliki Sifostratoudaki, Finja A. Ottink, Wassim Bou-Zeid, Roberta E. Ledda, Roqia F. Abul Kadir, Bushra Johari, Claire Fernandez, George W.J. Harston, Olivier Joly, Stephen Gerry, Anand Devaraj

“…Relationships between imaging biomarkers, lung function and survival were analysed. Results In separate test and validation cohorts, 168 and 176 patients with IPF respectively (median survival 2.6 years) were studied. …”
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A case of type 2 amiodarone-induced thyrotoxicosis by O. O. Soloviuk, R. L. Kulynych, O. A. Soloviuk

“…Iodine-induced thyrotoxicosis (IIT) is an abnormal function of the thyroid gland towards increasing caused by excessive iodine intakes of the body. …”
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Long-term indapamide retard therapy in adolescents with Stage I arterial hypertension by I. V. Logacheva, E. A. Gunicheva

“…In total, the study included 41 adolescent boys, aged 16-18 years, with Stage I AH (main group, MG), and 27 healthy adolescents (control group, CG). …”
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Acute high-intensity aerobic exercise affects brain-derived neurotrophic factor in mild cognitive impairment: a randomised controlled study by Emer M Guinan, Kate E Devenney, Áine M Kelly, Bibiana C Mota, Cathal Walsh, Marcel Olde Rikkert, Stefan Schneider, Brian Lawlor

“…Objective To investigate the brain-derived neurotrophic factor (BDNF) and cognitive response to a short bout of high-intensity aerobic exercise in older adults with mild cognitive impairment (MCI).Methods Participants were randomised to one of two testing schedules, completing either a standardised exercise test (group A) or a resting control condition (group B). …”
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Efficiency of gene therapy for sensorineural hearing loss in mouse model: A meta‐analysis by Nevra Keskin Yilmaz, Dogukan Ozen, Rafael da Costa Monsanto, Emre Ocak, Artur Koerig Schuster, Tomotaka Shimura, Sebahattin Cureoglu

“…Abstract Objectives Sensorineural hearing loss (SNHL) is a disorder characterized by the loss or impairment of cochlear hair cells or the auditory nerve. In recent years, gene therapy has emerged as a promising approach for SNHL treatment. …”
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Approbation of the mechanism of economic reliability on the example of an industrial enterprise by A. R. Terentyeva

“…To analyze the current state of an industrial enterprise, a generalized indicator of the level of economic reliability in dynamics over six years has been established using the desirability function. …”
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The effect of neoadjuvant chemoradiotherapy on whole-body physical fitness and skeletal muscle mitochondrial oxidative phosphorylation in vivo in locally advanced rectal cancer pat... by Malcolm A West, Lisa Loughney, Daniel Lythgoe, Christopher P Barben, Valerie L Adams, William E Bimson, Michael P W Grocott, Sandy Jack, Graham J Kemp

“…All patients underwent a cardiopulmonary exercise test and a phosphorus magnetic resonance spectroscopy quadriceps muscle exercise-recovery study before and after neoadjuvant chemoradiotherapy. …”
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Trimetazidine MB treatment in patients with chronic heart failure by T. E. Morozova, E. I. Ivanova

“…In 82 patients (67 men, 15 women), mean age 62,2±7,3 years, with CHD and Functional Class (FC) II-III CHF, the effects of 16-week complex therapy including trimetazidine MB (70 mg/d; Group I) vs. trimetazidine-free therapy (Group II) on CHF FC dynamics, left ventricular (LV) remodelling, physical stress tolerance, and myocardial bio-electric activity were investigated. …”
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EXercise to Prevent frailty and Loss Of independence in insulin treated older people with DiabetEs (EXPLODE): protocol for a feasibility randomised controlled trial (RCT) by James Shaw, Miles D Witham, Guy S Taylor, Daniel J West, Rachel Stocker

“…The aim of this feasibility randomised controlled trial is to (1) characterise the physical function, cardiovascular health and the health and well-being of older adults with mild frailty with/without diabetes treated with insulin, (2) to understand the feasibility and acceptability of a 4-week resistance exercise training programme in improving these parameters for those with diabetes and (3) to test the feasibility of recruiting and randomising the diabetic participant group to a trial of resistance training.Methods and analysis Thirty adults aged ≥60 years with insulin-treated diabetes mellitus (type 1 or 2), and 30 without, all with mild frailty (3–4 on the Rockwood Frailty Scale) will be recruited. …”
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The joint association between sleep quality, moderate-to-vigorous physical activity, cardiorespiratory fitness, and working memory in Chinese adolescents by Jun Hong, Yuan Liu, Yaru Guo, YuQiang Li, Feng Zhang, Pengwei Sun, Yanyan Hu, He Liu, Xiaojian Yin

“…Good sleep quality is significant in improving cognition function among Chinese adolescents.…”
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Role of protein intake in maintaining muscle mass composition among elderly females suffering from sarcopenia by Izwa Ishaq, Sana Noreen, Patrick Maduabuchi Aja, Ayomide Victor Atoki

“…Anthropometric parameters, including body mass (83.51 ± 4.23 kg) and waist circumference (113.90 ± 10.82 cm), showed notable enhancement in the moderately higher protein group. Muscle function and imaging assessments, such as handgrip strength and knee flexion, demonstrated improved functionality. …”
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Rationale and protocol for a safety, tolerability and feasibility randomized, parallel arm, double-blind, placebo-controlled, pilot study of a novel ketone ester targeting frailty... by Brianna J Stubbs, Gabriela Alvarez Azañedo, Sawyer Peralta, Stephanie Roa Diaz, Wyatt Gray, Laura Alexander, Wendie Silverman-Martin, Thelma Y Garcia, Traci M Blonquist, Vaibhav Upadhyay, Peter J Turnbaugh, James B Johnson, John C Newman

“…Exploratory outcomes include physical function, cognitive function, quality of life, aging biomarkers and inflammatory measures.…”
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Cdkn1c Boosts the Development of Brown Adipose Tissue in a Murine Model of Silver Russell Syndrome. by Matthew Van De Pette, Simon J Tunster, Grainne I McNamara, Tatyana Shelkovnikova, Steven Millership, Lindsay Benson, Stuart Peirson, Mark Christian, Antonio Vidal-Puig, Rosalind M John

“…The accurate diagnosis and clinical management of the growth restriction disorder Silver Russell Syndrome (SRS) has confounded researchers and clinicians for many years due to the myriad of genetic and epigenetic alterations reported in these patients and the lack of suitable animal models to test the contribution of specific gene alterations. …”
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A Rare Presentation of Whitmore’s Disease (Melioidosis) with Multisystem Abscess in a Diabetic Patient with Intractable Hiccups by Vuppala Rachana, Vignessh Raveekumaran

“…Hereby, authors report a case of a 63-year-old female with a known history of diabetes who presented with fever and hiccups for 40 days, deranged liver function tests, and leukocytosis. …”
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Effectiveness of different treatment regimens of enhanced external counterpulsation in patients with stable coronary artery disease complicated by heart failure by A. S. Lishuta, O. A. Slepova, N. A. Nikolaeva, N. V. Khabarova, E. V. Privalova, Yu. N. Belenkov

“…To study the effect of various therapy regimens with enhanced external counterpulsation (EECP) on exercise tolerance, quality of life, indices of structural and functional state of cardiovascular system in patients with stable coronary artery disease (CAD) complicated by chronic heart failure (CHF).Material and methods. …”
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MicroRNA expression levels in lung recipients: correlations with clinical and laboratory data by O. P. Shevchenko, S. O. Sharapchenko, O. M. Tsirulnikova, I. V. Pashkov, O. E. Gichkun, D. A. Velikiy, E. F. Shigaev, D. O. Oleshkevich, M. T. Bekov

“…The study included 57 lung recipients aged 10 to 74 years (35 ± 15), including six children (9%) – four boys 10, 12, 13 and 17 years and girls 13 and 14 years old – and 51 adult recipients, including 30 men (62.5%). …”
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Deprescribing anticholinergics to preserve brain health: reducing the risk of dementia through deprescribing (R2D2): study protocol for a randomized clinical trial by Noll L. Campbell, Richard J. Holden, Sujuan Gao, Frederick W. Unverzagt, Kathleen A. Lane, Allie Carter, Addison B. Harrington, Sneha Manoharan, Neha Manoharan, Danielle L. Rosenthal, Christopher Pitts, Kathryn Pelkey, Emily Papineau, David M. Lauck, Noha Keshk, Khalid Alamer, Hussein Khalil, Malaz A. Boustani

“…Participants will complete outcome assessments every 6 months up to 2 years by blinded outcome assessors. The primary outcome of the study is a composite measure of cognition that includes domains assessing executive cognitive function, language, and memory. …”
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Arthroscopic Knotless Double-Row Transosseous Equivalent Repair Is a Viable Option for Treatment of Large and Massive Rotator Cuff Tears by Patrick A. Massey, M.D., M.B.A., Lincoln Andre, M.D., Kevin Perry, M.D., D.P.T., Lindy Robichaux-Edwards, M.D., Rachel Kushner, M.D., Christopher Caldwell, M.D., Robert Rutz, M.D., Alberto Simoncini, M.D.

“…Minimum follow-up was 2 years. Clinical evaluation was performed using shoulder functionality tests, Constant score, and University of California, Los Angeles score. …”
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Sex differences in epigenetic ageing for older people living with HIVResearch in context by Carrie D. Johnston, Alina P.S. Pang, Eugenia L. Siegler, Charlene Thomas, Chelsie O. Burchett, Mia Crowley, Rochelle O'Brien, Lishomwa C. Ndhlovu, Marshall J. Glesby, Michael J. Corley

“…We profiled plasma biomarkers with Olink high-throughput proteomics to test associations with epigenetic age acceleration. …”
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Decreased Muscle Strength in Children With Repaired Tetralogy of Fallot: Relation With Exercise Capacity by Graziëlla Eshuis, Hiske van Duinen, Otto T. H. M. Lelieveld, Anneke K. Hegeman, Hessel Nijenhuis, Tineke P. Willems, Ann M. Hepping, Natasha Maurits, Gideon J. du Marchie Sarvaas, Rolf M. F. Berger

“…Exclusion criteria comprised the following: Down syndrome, unstable pulmonary disease and severe scoliosis affecting pulmonary function, neuromuscular disease, and mental or physical limitations that prohibit the execution of the functional tests. …”
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