The Influence of Emphysema on Treatment Response to Biologic Therapy in Severe Asthma by Biener L, Morobeid H, Pizarro C, Kuetting D, Nickenig G, Skowasch D

“…Half (43, 50.0%) were never-smokers, half ex-smokers with an average of 26.9 ± 18.2 pack-years. Patients with ≥ 5% emphysema were more often ex-smokers (80% vs 41%, p=0.002), had poorer lung function (FEV1 median 1.3 [interquartile range: 1.0;1.6] vs 1.8[1– 2;2.4] L, p=0.037), and more comorbid COPD (50% vs 21%, p=0.012). …”
Get full text

Autoimmune hepatitis developed after acute liver failure due to hepatitis A. A case-report by Reina S. Velez-Ramirez, Yenni Joseline Cruz-Ramirez, Francisco I. Garcia-Juarez

“…Results: 27 days after initial evaluation, fatigue and fever of unknown origin were present. Liver function test with BT 25.58 mg/dl, BD 17.55.0 mg/dl, ALT 38 U/l, AST 100 U/l and ALP 105 U/l and INR 1.5. …”
Get full text

DETERMINATION OF CHEWING EFFICIENCY IN PATIENTS WITH RESTORED TOOTH CROWN PART by V.V. Nikolov, D M. Korol, D.D. Kindiy, M.D. Korol

“…While the dynamics of mastication test changes in sample group 2 looked as follows. …”
Get full text

Heart failure induced by a tumor in a young adult woman: A case report of dilated cardiomyopathy triggered by paraganglioma by Hamza El Abidi, Ahmed Ibrahimi, Mohamed Ali Mikou, Imane Iraqui, Imad Boualaoui, Zined Labbi, Sabrine Derqaoui, Zakiya Bernoussi, Hashem El Sayegh, Yassine Nouini

“…Paragangliomas are rare neuroendocrine tumors that can secrete catecholamines, resulting in cardiovascular consequences such as catecholamine-induced cardiomyopathy and heart failure.The pathogenesis involves excessive catecholamine exposure, which causes myocardial damage, decreased cardiac function, and systemic consequences. We discuss the case of a 26-year-old adult woman who presented with dyspnea, orthopnea, and lower limb edema and was finally diagnosed with dilated cardiomyopathy. …”
Get full text

Exercise program to reduce the risk of cognitive decline and physical frailty in older adults: study protocol for an open label double-arm clinical trial by Moeko Noguchi-Shinohara, Kunihiko Yokoyama, Junji Komatsu, Junji Komatsu, Kazumi Masuda, Mitsunobu Kouno, Mitsuhiro Yoshita, Kenjiro Ono

“…The trial will include a physical exercise training program (once a week) and nutritional lectures (once a month) over 5 months and follow-up for ≥1 year. The primary endpoint is the program’s efficacy in preventing cognitive decline, as assessed by changes in the memory performance index of the mild cognitive impairment (MCI) screen; the secondary endpoints are the incidence of MCI and dementia, physical testing, and frailty proportion. …”
Get full text

Acute pulmonary embolism treatment in lung transplant recipients: mechanical thrombectomy and catheter directed thrombolysis by Ahmad Arar, Samuel L. Rice, Mhd Wisam Alnablsi, Akhilesh Pillai, Jamaal Benjamin, Rehan Quadri, Daniel Lamus, Anil Pillai

“…Follow-up assessments encompassed a minimum of one year and up to 3 years post-treatment, evaluating various parameters including ICU stay, ventricular pressures, pulmonary function, and laboratory tests. …”
Get full text

The impact of herd age structure on the performance of commercial sow-breeding farms by Santos Sanz-Fernández, Cipriano Díaz-Gaona, João Simões, José Carlos Casas-Rosal, Nuria Alòs, Llibertat Tusell, Raquel Quintanilla, Vicente Rodríguez-Estévez

“…Results Farms are classified into three groups according to the quadratic function fitted to the percentage of sows by parities. …”
Get full text

Do Patients with Prior Distraction Arthroplasty Fare Worse after Total Ankle Replacement? by Allison Boden MD, Kira Lu, Emily Teehan MS, Jensen Henry MD, Constantine Demetracopoulos MD

“…Statistically significant differences in PROMIS scores at 2-year follow-up were detected using non-parametric Mann-Whitney U tests. …”
Get full text

Chemotherapy-Induced Unconjugated Hyperbilirubinemia Complicated by Other Trigger Factors in a Child with T-Cell Acute Lymphoblastic Leukaemia and <i>UGT1A1</i> Mutation-Associated... by Mohammad Shukri Khoo, Sharifah Naiema Jamalullail, C-Khai Loh, Sie Chong Doris Lau, Hamidah Alias

“…We present the case of a 15-year-old male who was diagnosed with T-ALL and treated with a chemotherapy regimen following the modified Dutch Child Oncology Group ALL-9 (High Risk) protocol. …”
Get full text

Identification of the First De Novo UBIAD1 Gene Mutation Associated with Schnyder Corneal Dystrophy by Benjamin R. Lin, Ricardo F. Frausto, Rosalind C. Vo, Stephan Y. Chiu, Judy L. Chen, Anthony J. Aldave

“…A slit lamp examination was performed on a 47-year-old woman without a family history of corneal disorders. …”
Get full text

Effectiveness of Bobath Therapy vs. Conventional Medical Gymnastics in Psycho-Social and Cognitive Status Improvement in Children with Mild Neurodevelopmental Delay: A Randomized D... by Zrinka Djukić Koroljević, Luka Bulić, Eva Brenner, Matea Bračić, Petar Brlek, Dragan Primorac

“…<b>Methods:</b> The study included 100 children up to 3 months of age who were diagnosed with a mild neuromotor disorder based on clinical examination, the Münich Functional Developmental Diagnostic Test for the first year of life, and the Ages and Stages questionnaire. …”
Get full text

Vertical Stratification of Butterfly Assemblages Persists in Highly Disturbed Forest Fragments of the Brazilian Atlantic Forest by Denise B. Silva, André V. L. Freitas, Oscar F. Junior, Jessie P. Santos

“…We hypothesized that degraded forests would not exhibit vertical stratification due to the low variation in the microhabitat conditions along the vertical gradient, resulting from the canopy openness. To test this, we sampled fruit-feeding butterflies with bait traps, alternately disposed between the understory and canopy of three secondary forest fragments in a very fragmented Atlantic Forest landscape, for one year. …”
Get full text

Atrial fibrillation in patients with dilated cardiomyopathy: prevalence, risk factors and prognostic significance by T. G. Vaikhanskaya, T. A. Dubovik, O. D. Levdansky, T. V. Kurushko, N. G. Danilenko

“…Compared with patients maintaining sinus rhythm, patients with AF were older (51,4±10 vs  43,6±13 years, p=0,001) and had lower exercise tolerance (6-minute walk test: 379±45 vs 445±43 meters; p=0,0002) and a higher heart failure functional class (NYHA class III-IV: 38/50,7% vs 52/26,7%; χ2=13,6; p=0 ,0003). …”
Get full text

The Use of High-Density SNP Array to Map Homozygosity in Consanguineous Families to Efficiently Identify Candidate Genes: Application to Woodhouse-Sakati Syndrome by Molly B. Sheridan, Elizabeth Wohler, Denise A. S. Batista, Carolyn Applegate, Julie Hoover-Fong

“…Two consanguineous Qatari siblings presented for evaluation: a 17-4/12-year-old male with hypogonadotropic hypogonadism, alopecia, intellectual disability, and microcephaly and his 19-year-old sister with primary amenorrhea, alopecia, and normal cognition. …”
Get full text

Ain’t No Sunshine When She’s Gone: Pseudohypoparathyroidism Discovered in an Adult by C. R. van Rooijen, M. B. Kok, S. Simsek, F. Stam

“…The diagnosis is confirmed by the Ellsworth-Howard test, which will show a 100-fold increase in phosphate excretion if the PTH receptor functions properly. …”
Get full text

Stent-induced hypersensitivity leading to refractory in-stent restenosis: a case report by Menghuai Ma, Jiong Tang

“…Although the cardiovascular risk factors were well-controlled, the patient developed four episodes of acute myocardial infarction with in-stent restenosis within 1 year. Intravascular ultrasound revealed diffuse neointimal hyperplasia in the in-stent restenosis lesion, and the blood tests showed no sign of systemic inflammation or infection. …”
Get full text

Outcome of enzyme replacement therapy for hematological and visceral manifestations in children with acid sphingomyelinase deficiency: a single center experience in upper Egypt by Mervat A. M. Youssef, Esraa Hefzy Shaker, Nahed A M Saleh

“…Methods Ten children with ASMD (five with type B and five with type A/B) received ERT for one year. Growth parameters, complete blood counts, abdominal ultrasonography, liver function tests, lipid profiles, and neurological assessments were conducted at baseline and subsequently every three months. …”
Get full text

Strongyloidiasis mimics duodenal lymphoma in a patient with systemic lupus erythematosus and antiphospholipid syndrome: a case report by Ayoub Basham, Sanaz Soleimani, Atash Ab Parvar, Arash Rahimi, Ebrahim Evazi, Seyed Hamid Moosavy

“…Liver enzymes as well as renal function tests were within the normal range. Stool examination was negative for trophozoites, ova, or cysts of parasites. …”
Get full text

The effects of normal and interrupted sleep combined with acute caffeine supplementation on some immune system indices and anaerobic power in male athletes by Mohammad hossein Hashemzadeh, Farhad Rahmaninia, Payam Saidie

“…Fourteen male athletes (mean±SD; age, 22.92±1.32 years; height, 176.4±4.38 cm; weight, 71.42±9.65 kg) participated in this study. …”
Get full text

Analyses exploratoires dendrochronologique et dendro-isotopique des ripisylves de la rivière Milo (Guinée) by Soumaïla Condé, Thierry Otto, Issam Moussa, Luc Lambs, Dov Corenblit

“…This study shows that it is possible to estimate the age (15 to 102 years) and radial growth rates (0.26 to 1.39 cm/year) for species with discernible rings. …”
Get full text