MULTICENTER DOUBLE-BLIND RANDOMIZED PLACEBO-CONTROLLED TRIAL OF THE SYMPTOM- AND STRUCTURE-MODIFYING EFFECT OF ALFLUTOP IN PATIENTS WITH KNEE OSTEOARTHROSIS. COMMUNICATION 1. EVA... by Lyudmila Ivanovna Alekseeva, E P Sharapova, E A Taskina, N V Chichasova, G R Imametdinova, N A Shostak, N G Pravdyuk, L N Denisov

“…The patients were randomly assigned to two groups: 1) 45 patients who received alflutop as 1-ml intramuscular injections for a 20-day cycle at a 6-month interval for 2 years (a total of 4 cycles during 2 years); 2) 45 patients who were given PL (isotonic sodium chloride) injections following the same pattern. …”
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Influences of mountain closure on community composition of ecological service forest in Fuyang, Hangzhou, China by ZHANG Jun, XU Shenghua, WU Chuping, JIAO Jiejie, HUANG Yujie, GAO Hongdi, SHEN Aihua, YUAN Weigao, ZHU Jinru, GAO Zhihui, JIANG Bo

“…According to basic characteristics (e. g., distribution pattern, forest type) of the ecological service forest in Fuyan, Hangzhou, China, we aimed to understand the changes in community composition, stand quality, and secondary succession process after the mountain closure. …”
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An impact of neutrophil extracellular traps to the prothrombotic state and tumor progression in gynecological cancer patients by E. V. Slukhanchuk, V. O. Bitsadze, A. G. Solopova, J. Kh. Khizroeva, N. D. Degtyareva, D. V. Shcherbakov, J.-C. Gris, I. Elalamy, A. D. Makatsariya

“…One of the leading causes in the mortality pattern of cancer patients is accounted for by thrombotic complications. …”
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Hábitos bucales deformantes en niños de tres a cinco años de edad de la Policlínica Mario Gutiérrez Ardaya by Roger J Reynaldo González, Jorge L Bello Jerez, Dolores M Cejas Prieto

“…Abnormal habits that can interfere with the normal pattern of facial growth, should be distinguished from normal unwanted habits, which should worry are those who may be involved in the etiology of malocclusions. …”
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Identification of key enzymes in lignocellulose biosynthesis from dynamic observations in maize stalks by Xiaoxu Zhan, Fanlei Kong, Qinlin Liu, Tianqiong Lan, Fan Liu, Xinglong Wang, Xia Du, Xiang Chen, Jichao Yuan

“…However, the key enzymes, critical MYB transcription factors, and their dynamic alterations pattern under natural field circumstances are still unknown. …”
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MiRNA-mRNA integration analysis of three continuous embryonic stages of Chinese horseshoe crab Tachypleus tridentatus by Yunfan Huang, Ying Qiao, Shengping Zhong, Xingzhi Zhang, Menghong Hu, Kityue Kwan, Theerakamol Pengsakul, Jiasen Guo, Xuyang Chen, Xiaowan Ma, Qiongzhen Li

“…Horseshoe crabs are marine chelicerates which have existed for about 450 million years. Their long coexistence with microbial pathogens presumably is due to their efficient immune system. …”
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Applying evidence-based cross-disciplinary concepts helps to explain the heterogeneity in pain, function, and biological measures in individuals with knee pain with/at risk of oste... by Angela M. Mickle, Jared J. Tanner, Udell Holmes, III, Ahmed Rashid, Olivier Barolette, Brittany Addison, Nicola Sambuco, Cynthia Garvan, Song Lai, Christoph Seubert, Siegfried Schmidt, Roland Staud, Jeffrey C. Edberg, David Redden, Burel R. Goodin, Catherine C. Price, Roger B. Fillingim, Kimberly T. Sibille

“…Although not significant, the clinical composite measure aligned with the other outcome measures and demonstrated the hormesis inverted U pattern. Conclusions:. Groups based on dispositional traits and socioeconomic status explain differing clinical outcomes. …”
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Parvovirus B19 Infection in Pregnancy: Awareness of the Increased Incidence of Severe Intrauterine Infection by Eleonora Torcia, Alessandra Familiari, Elvira Passananti, Maria Vittoria Alesi, Giulia di Marco, Federica Romanzi, Marco De Santis, Tullio Ghi, Elisa Bevilacqua

“…Typically, B19V follows a well-documented seasonal pattern, with annual epidemics peaking in the spring and larger outbreaks occurring approximately every four years. …”
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Efficacy and safety of direct oral anticoagulants compared with warfarin in antiphospholipid syndrome. Results of a multicenter retrospective cohort study by Maha A.T. Elsebaie, Zoe Wickham, Stephanie DeBragga, Stacey Fedewa, Mohamed Amgad, Jane Jungyoon Park, Allen Li, Ali Eshaghpour, Juan Li, Mark Crowther, Manila Gaddh

“…Objectives: This multicenter, retrospective cohort study conducted at Emory and McMaster University Medical Centers aimed to explore pattern of DOAC use among APS patients and compare the efficacy and safety of DOACs vs warfarin. …”
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Numerical Simulation of Frost Heave and Thaw Settlement Characteristics in a Complex Pipe–Soil System in the Seasonally Frozen Ground by Qinglin Li, Pengrui Feng, Rui Wang, Ni An, Ruiguang Bai, Guang Yang, Xinlin He, Ping Lin, Zixu Hu

“…By employing coupled thermal–hydraulic–mechanical (THM) simulation methods, the study analyzed the changes in volumetric water content, volumetric ice content, moisture migration patterns, and temperature field distribution of a water pipeline after three years of service under real engineering conditions in the cold region of northern Xinjiang, China. …”
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Acute alcohol intoxication among adolescents in Italy, the Netherlands and Belgium: a cross-national hospital chart comparison study by Stijn Verhulst, Nico van der Lely, Andrea Orsi, Giancarlo Icardi, Guido Van Hal, Hanna van Roozendaal, Louise Pigeaud, Allegra Ferrari, Loes de Veld, Inge Glazemakers, Jozef De Dooy

“…Comprehensive data on adolescent drinking patterns is crucial for developing effective prevention strategies. …”
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Dynamics of Nocturnal Evapotranspiration in a Dry Region of the Chinese Loess Plateau: A Multi-Timescale Analysis by Fengnian Guo, Dengfeng Liu, Shuhong Mo, Qiang Li, Fubo Zhao, Mingliang Li, Fiaz Hussain

“…Evapotranspiration (<i>ET</i>) is an important part of agricultural water consumption, yet little is known about nocturnal evapotranspiration (<i>ETN</i>) patterns. An eddy covariance system was used to observe <i>ET</i> over five consecutive years (2020–2024) during the growing season in a dry farming area of the Loess Plateau. …”
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Prediction Modeling and Driving Factor Analysis of Spatial Distribution of CO₂ Emissions from Urban Land in the Yangtze River Economic Belt, China by Chao Wang, Jianing Wang, Le Ma, Mingming Jia, Jiaying Chen, Zhenfeng Shao, Nengcheng Chen

“…In recent years, China’s urbanization has accelerated, significantly impacting ecosystems and the carbon balance due to changes in urban land use. …”
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Association between the Balanced Healthy Eating Index and depression and the mediating role of extreme pessimistic thoughts: an analysis from the health and nutrition database by Yantong Liu, Yantong Liu, Shengyong Bao, Chuang Li, Feifei Li, Mingqian Liang, Guang Yang

“…Future longitudinal studies are warranted to clarify causal pathways and to determine whether improving dietary patterns or mitigating extreme pessimism could reduce depression prevalence.…”
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Impact of resin tapping on the radial growth and climate sensitivity of naturally- regenerated Pinus roxburghii (Chir pine) in Western Nepal by Bipin Bhattarai, Narayan Prasad Gaire, Tek Maraseni, Bishnu Prasad Devkota, Badri Bhattarai, Shankar Tripathi, Kamal Raj Aryal, Hari Adhikari

“…A tree-ring width chronology spanning 52 years was developed for both tapped and untapped trees. …”
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Impact of Artificial Intelligence on Customer Relationship Management: a Bibliometric Analysis by Aleksy Kwilinski, Nataliia Trushkina, Yuliia Remyha, Tamila Patlachuk

“…Therefore, the purpose of this article is to identify the relationship between artificial intelligence and customer relationship management by characterizing the evolution of key patterns of scientific publications on this problem. …”
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Has the Three Gorges Reservoir Impacted Regional Moisture Recycling? by Jia Wei, Weiguang Wang, Mingzhu Cao, Jianyun Zhang, Junliang Jin, Guoqing Wang, Hongbin Li, Xiaolong Pan, Zongchao Ye, Adriaan J. Teuling, Shuo Wang

“…However, with the role of the Three Gorges Reservoir (TGR) in narrowing temperature ranges and changing precipitation patterns is well understood, its impact on moisture recycling is little known. …”
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Visualization analysis of breast cancer-related ubiquitination modifications over the past two decades by Yongxiang Li, Yiyang Wang, Yubo Jing, Youseng Zhu, Xinzhu Huang, JunYi Wang, Elihamu Dilraba, Chenming Guo

“…This research aimed to investigate the evolution patterns, key areas of interest, and future directions of ubiquitination in breast cancer via bibliometric analysis. …”
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Injuries in German national short-track speed skating athletes by Jan Ziegler, Heidrun Beck, Roland L. Bell, Dominik Matzner, Xinggui Tian, Stefan Zwingenberger

“…Important information about career-related injuries and injury patterns resulted from the analyses. However, further prospective research is needed to support the prevention of health issues in STSS.…”
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Nitrogen fertilizer reduction based on bioorganic fertilizer improves the yield and quality of fresh leaves of alpine tea in summer by Rui Shi, Ying Wang, Fangyu Zhou, Sadam Hussain, Xingyu Lei, Enxiang Chen, Cong Wang, Juan Bai, Chunmei Gong

“…Herein, a field experiment was conducted to explore appropriate fertilization patterns for alpine tea plantations in southern Shaanxi (China). …”
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