Association of genetic risk of Alzheimer’s disease and cognitive function in two European populations by Biqi Wang, Lori B. Chibnik, Seung Hoan Choi, Deborah Blacker, Anita L. DeStefano, Honghuang Lin

“…We developed the AD PRS (excluded the APOE variants) in the middle age UK Biobank participants (age ranged 39–72, mean age 57 years) of European ancestries by LDpred2. To validate the association of AD PRS and cognitive function internally in the UK Biobank, we linearly regressed standardized cognitive function on continuous standardized AD PRS with age at cognitive test, sex, genotyping array, first 10 principal components of genotyping, smoking, education in years, body mass index, and apolipoprotein E gene ε4 (APOE4) risk allele dosages. …”
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Participation and quality of life of Nepalese children with visual impairment in comparison with normally sighted peers: a cross sectional comparative study by Srijana Adhikari, Ellen Bernadette Maria Elsman, Ruth Marie Antoinette van Nispen, Fleur Van Rens, Manish Poudel, Gerardus Hermanus Maria Bartholomeus van Rens

“…Conclusion Younger children with blindness showed worse participation and quality of life compared to children with VI, whereas results for older children showed a mixed pattern with children with blindness showing better participation in psychosocial domain. …”
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«No-reflow» phenomenon and risk factors associated with its development after primary percutaneous coronary interventions in patients with ST elevation myocardial infarction by V.І. Tseluyko, M.M. Doloh, O.A. Leonenko

“…The age of the patients was 36 to 85 years, mean age 60.4 ± 2.03 years. PCI was performed immediately after the diagnosis of STEMI, an average 7.6 ± 1.2 hours after onset of the first symptoms. …”
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Land Use/Land Cover Change Impact on Hydrological Process in the Upper Baro Basin, Ethiopia by Tewodros Getu Engida, Tewodros Assefa Nigussie, Abreham Berta Aneseyee, John Barnabas

“…Landsat images were used to classify the LU/LC pattern using ERDAS Imagine 2014 software and the LU/LC were classified using the Maximum Likelihood Algorithm of Supervised Classification. …”
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New Therapeutic Options for Fusariosis: A Patent Review (2008–2023) by Izadora Dillis Faccin, Túlio Máximo Salomé, Gleyce Hellen de Almeida de Souza, Leonardo da Costa Xavier, Izabel Almeida Alves, Vanessa Castro Felix Lima, Fabíola Lucini, Simone Simionatto, Luana Rossato

“…The disease presents several clinical manifestations and epidemiological patterns. Current treatment relies on azoles and polyenes, but increasing antifungal resistance requires the exploration of new therapeutic options. …”
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Antibiotic Resistance Microbiology Dataset (ARMD): A Resource for Antimicrobial Resistance from EHRs by Fateme Nateghi Haredasht, Fatemeh Amrollahi, Manoj V. Maddali, Nicholas Marshall, Stephen P. Ma, Lauren N. Cooper, Andrew O. Johnson, Ziming Wei, Richard J. Medford, Sanjat Kanjilal, Niaz Banaei, Stanley Deresinski, Mary K. Goldstein, Steven M. Asch, Amy Chang, Jonathan H. Chen

“…Key attributes include organism identification, susceptibility patterns for 55 antibiotics, implied susceptibility rules, and de-identified patient information. …”
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Detectable use of ENSO information on crop production in Southern Africa by Erin Coughlan de Perez, Weston Anderson, Eunjin Han, Gibbon Innocent Tirivanhu Masukwedza, Ntlele Mphonyane

“…Similarly, we find that in both Lesotho and most provinces of South Africa, drought years associated with El Niño have worse yields than drought years that are not associated with El Niño (controlling for rainfall). …”
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Age-related gait adaptations: analysis of temporal gait parameters and variability, and muscle activation across flat vs. uneven surfaces in young, middle-aged, and older adults by Thomas B. Inns, Ilaria Pina, Lewis James Macgregor, Paul A. Dudchenko, Rachel A. Crockett, Angus Murray Hunter, Angus Murray Hunter, Angus Murray Hunter

“…This study investigated age-related differences in gait parameters and muscle activation across young (18–39 years), middle-aged (40–59 years), and older adults (60+ years) on flat and uneven surfaces.MethodsEighty-three healthy adults participated in the study. …”
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Borderline Personality Disorder: a narrative review on effective psychotherapies by Marina Neri, Antonino Reitano, Lavinia Rinnone, Antonio Bruno, Fabrizio Turiaco, Felicia Matilde Ferreri, Carmela Mento, Maria Rosaria Anna Muscatello, Fiammetta Iannuzzo

“…Borderline personality disorder (BPD) is a severe mental disorder characterized by pervasive patterns of relational instability, chronic feelings of emptiness, sense of abandonment, self-injurious and anticonservative attempts. …”
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Monitoring water clarity of lakes in the Middle-Lower Yangtze Plain using Landsat observations (1984–2023) by Miaomiao Chen, Fei Xiao, Zhou Wang, Yadong Zhou, Wangzheng Shen, Qi Feng, Enhua Li, Yun Du

“…The water clarity changes of these 17 lakes have a clear seasonal variation pattern, with the highest in summer and the lowest in winter. …”
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Accelerated increase in ferritin levels during menopausal transition as a marker of metabolic health by Minjeong Kim, Yoosoo Chang, Yoosun Cho, Min-Jung Kwon, Hee-Kyung Joh, Ga-Young Lim, Ria Kwon, Jiin Ahn, Jungeun Park, Kye-Hyun Kim, Jae Keun Yoo, Seungho Ryu

“…Abstract Despite ferritin’s role in iron and metabolic health, its timing and pattern of change relative to other iron biomarkers during the menopausal transition remain unclear, as blood loss shifts alter iron metabolism. …”
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Investigation of the effect of deprivation on the burden and management of venous leg ulcers: a cohort study using the THIN database. by Emily S Petherick, Nicky A Cullum, Kate E Pickett

“…<h4>Background</h4>There has been limited examination of the contribution of socio-economic factors to the development of leg ulcers, despite the social patterning of many underlying risk factors. No previous studies were found that examined social patterns in the quality of treatment received by patients with leg ulcers.…”
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Prevalence of Thyroid Dysfunction and Antithyroid Antibodies in North India by Cherry Bansal, Amanpreet Singh, Pragya Pandey

“…For data analysis, the study population was grouped into hypothyroid (low FT3, low FT4, and high TSH), hyperthyroid (high FT3, high FT4, and low TSH), and others – including all other biochemical patterns. Statistical analysis was done using the IBM-SPSS software, version 20. …”
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A novel bladder cancer surveillance schedule using bladder Cx for patients on annual surveillance by Arjun Guduguntla, Thomas Whish‐Wilson, Lauren Chandler, Dennis Gyomber

“…In this program, eligible patients alternate between yearly surveillance cystoscopy and CxM, instead of the standard yearly surveillance cystoscopy. …”
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Prevalence and Risk of Immunostimulatory Herbal Supplement Treatment Among Autoimmune Dermatology Patients by Daniella F. Faden, Caroline J. Stone, Lillian Xie, Lais Lopes Almeida Gomes, Victoria P. Werth

“…Objective We assess the prevalence and patterns of herbal supplement treatment among patients with autoimmune skin diseases, particularly dermatomyositis (DM) and cutaneous lupus erythematosus (CLE), and identify commonly taken supplements and their associated risks. …”
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Community-acquired urinary tract infections: Causative agents and their resistance to antimicrobial drugs by Đorđević Zorana, Folić Marko, Janković Slobodan

“…Choice of antibiotics for treatment of UTIs should be governed not only by the local resistance patterns, but also by gender and age of patients.…”
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Therapeutic Needs of Older Adults with Inflammatory Bowel Disease (IBD): A Systematic Review by Suja P. Davis, Rachel McInerney, Stephanie Fisher, Bethany Lynn Davis

“…<b>Background/Objective:</b> Inflammatory bowel disease (IBD) diagnosis in the elderly falls under two categories: those diagnosed at a younger age and transitioning to the elderly group (>60 years) and those diagnosed at ≥60 years of age. Although it is difficult to calculate the incidence of IBD among elderly adults precisely, it is estimated that around 10–15% of IBD in the US are diagnosed after 60 years, and approximately 13% of IBD cases are diagnosed after the age of 65 globally. …”
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Magnetic Resonance Imaging findings in pediatric patients with Epilepsy: a single-center experience from Pakistan by Rehana Shaikh, Saba Sohail, Sabiha Zaheer

“…RESULTS: Of the 173 subjects, 94 (54.3%) were boys and 79 (45.7%) were girls, with mean age of 6.7±3.3 years. Generalized seizures were predominant (n=103; 59.5%), followed by focal seizures (n=57; 33%), and unknown seizure patterns (n=13; 7.5%). …”
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Improving old-age mortality estimation with parental survival histories in surveys by Bruno Masquelier, Ashira Menashe-Oren, Benjamin-Samuel Schlüter, Atoumane Fall, Stephane Helleringer

“…BACKGROUND: In many low- and middle-income countries, the mortality of adults over 50 years of age is poorly monitored because death registration systems are deficient. …”
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Disease burden and cost of hidradenitis suppurativa: a retrospective examination of US administrative claims data by Jessica Marvel, Anna Vlahiotis, Amy Sainski-Nguyen, Tina Willson, Alexandra Kimball

“…We examined demographic/clinical characteristics of patients with HS and treatment patterns, prevalence and healthcare resource utilisation/expenditures related to HS in the real-world.Design Retrospective claims data of MarketScan Commercial, Medicare Supplemental and Medicaid databases (2009–2014).Setting USA.Participants Patients aged ≥12 years with ≥3 non-diagnostic outpatient or inpatient claims with an HS diagnosis code and ≥12 months continuous enrolment with medical and pharmacy benefits before (preindex) and after (postindex) the earliest diagnosis of HS (index) were included.Results There were 11 325 Commercial/Medicare patients (mean age 37.4 years) and 5164 Medicaid patients (mean age 28.3 years). …”
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